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10.3923/pjbs.2020.119.125

http://scihub22266oqcxt.onion/10.3923/pjbs.2020.119.125
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suck abstract from ncbi


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pmid31944070      Pak+J+Biol+Sci 2020 ; 23 (2): 119-125
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  • Common Co-morbidities Are Challenging in the Diagnosis of Middle East Respiratory Syndrome (MERS-CoV) in Saudi Arabia #MMPMID31944070
  • Mohamed RAEH; Aleanizy FS; Alqahtani FY; Alanazi MS; Mohamed N
  • Pak J Biol Sci 2020[Jan]; 23 (2): 119-125 PMID31944070show ga
  • BACKGROUND AND OBJECTIVE: Middle East respiratory syndrome coronavirus (MERS-CoV) is a relatively recent human disease reported initially in Saudi Arabia in September, 2012. Morbidities investigation includes a process of excluding other possible options until certain suspected cases are confirmed. MATERIAL AND METHODS: In this study, we formulated a model under the authorization of the Saudi Ministry of Health to accurately identify cases among admitted suspected cases depending on specific signs and symptoms. Real-time polymerase chain reaction was used for confirmation of the positive cases. RESULTS: The results showed that the number of patients with combined symptoms of fever/sore throat and fever/cough/SOB was significantly higher in confirmed cases than in non-confirmed cases (p<0.05). Besides, the number of confirmed MERS-CoV cases was significantly higher among cases included in the study than excluded cases. It was also clearly demonstrated that fever combined with other symptoms represents 60% of the confirmed cases, which is significantly higher than for cases with other combined symptoms (p<0.0001). CONCLUSION: To the best of our knowledge, there are no appropriate diagnostic models that can differentiate human MERS-CoV infection among other respiratory infections. Therefore, we recommend the adoption of this newly established model of MERS-CoV to short- list corona suspected cases in Saudi Arabia.
  • |Comorbidity[MESH]
  • |Coronavirus Infections/*diagnosis/epidemiology/virology[MESH]
  • |Diagnosis, Differential[MESH]
  • |Host-Pathogen Interactions[MESH]
  • |Humans[MESH]
  • |Middle East Respiratory Syndrome Coronavirus/*isolation & purification/pathogenicity[MESH]
  • |Predictive Value of Tests[MESH]


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