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10.3390/v12010083 http://scihub22266oqcxt.onion/10.3390/v12010083 31936749!7019228!31936749     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Viruses 2020 ; 12 (1): ä Nephropedia Template TP {{tp|p=31936749|t=2020. A Tale of Two Viruses: The Distinct Spike Glycoproteins of Feline Coronaviruses |pdf=|usr=}}{{31936749}} gab.com Text A Tale of Two Viruses: The Distinct Spike Glycoproteins of Feline Coronaviruses JO: Viruses http://www.kidney.de/pget.php?&tw=1&pmid=31936749 #FOAvip Feline coronavirus (FCoV) is a complex viral agent that causes a variety of clinical manifestations in cats, commonly known as feline infectious peritonitis (FIP). It is recognized that FCoV can occur in two different serotypes. However, differences in the S protein are much more than serological or antigenic variants, resulting in the effective presence of two distinct viruses. Here, we review the distinct differences in the S proteins of these viruses, which are likely to translate into distinct biological outcomes. We introduce a new concept related to the non-taxonomical classification and differentiation among FCoVs by analyzing and comparing the genetic, structural, and functional characteristics of FCoV and the FCoV S protein among the two serotypes and FCoV biotypes. Based on our analysis, we suggest that our understanding of FIP needs to consider whether the presence of these two distinct viruses has implications in clinical settings. Twit Text FOAVip A Tale of Two Viruses: The Distinct Spike Glycoproteins of Feline Coronaviruses ????Viruses http://www.kidney.de/pget.php?&tw=1&pmid=31936749 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=31936749 #FOAvip English Wikipedia <ref>{{Cite pmid|31936749}}</ref> A Tale of Two Viruses: The Distinct Spike Glycoproteins of Feline Coronaviruses #MMPMID31936749 Jaimes JA; Millet JK; Stout AE; Andre NM; Whittaker GR Viruses 2020[Jan]; 12 (1): ä PMID31936749show ga Feline coronavirus (FCoV) is a complex viral agent that causes a variety of clinical manifestations in cats, commonly known as feline infectious peritonitis (FIP). It is recognized that FCoV can occur in two different serotypes. However, differences in the S protein are much more than serological or antigenic variants, resulting in the effective presence of two distinct viruses. Here, we review the distinct differences in the S proteins of these viruses, which are likely to translate into distinct biological outcomes. We introduce a new concept related to the non-taxonomical classification and differentiation among FCoVs by analyzing and comparing the genetic, structural, and functional characteristics of FCoV and the FCoV S protein among the two serotypes and FCoV biotypes. Based on our analysis, we suggest that our understanding of FIP needs to consider whether the presence of these two distinct viruses has implications in clinical settings. |Animals[MESH] |Cats[MESH] |Coronavirus, Feline/*genetics/metabolism/pathogenicity[MESH] |Feline Infectious Peritonitis/metabolism/*virology[MESH] |Membrane Fusion[MESH] |Models, Molecular[MESH] |Receptors, Virus/metabolism[MESH] |Serogroup[MESH] |Species Specificity[MESH]A Tale of Two Viruses: The Distinct Spike Glycoproteins of Feline Coro(epmc).pdf DeepDyve Pubget Overpricing