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suck abstract from ncbi


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pmid3189965      Ann+Allergy 1988 ; 61 (5): 388-91
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  • Acute effect of intravenous magnesium sulfate on airway obstruction of asthmatic patients #MMPMID3189965
  • Rolla G; Bucca C; Caria E; Arossa W; Bugiani M; Cesano L; Caropreso A
  • Ann Allergy 1988[Nov]; 61 (5): 388-91 PMID3189965show ga
  • The bronchodilating effect of magnesium sulfate (MgSO4) was studied in ten asthmatic patients with moderate to severe airway obstruction. Two grams of MgSO4 or saline in double-blind crossover design was administered IV for 20 minutes (0.40 mmol/min) and forced expiratory capacity and forced expiratory volume in one second (FEV1) were studied at intervals. Only at the end of MgSO4 infusion did FEV1 increase significantly (109% of initial values). The bronchodilating effect was short lasting and far less than that observed after salbutamol.
  • |Adult[MESH]
  • |Airway Obstruction/drug therapy[MESH]
  • |Asthma/*physiopathology[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Injections, Intravenous[MESH]
  • |Magnesium Sulfate/*administration & dosage[MESH]
  • |Magnesium/blood[MESH]
  • |Male[MESH]


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