Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1007/978-1-0716-0211-9_16 http://scihub22266oqcxt.onion/10.1007/978-1-0716-0211-9_16 31883098!7123785!31883098     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Methods+Mol+Biol 2020 ; 2099 (ä): 205-220 Nephropedia Template TP {{tp|p=31883098|t=2020. Histopathologic Evaluation and Scoring of Viral Lung Infection |pdf=|usr=}}{{31883098}} gab.com Text Histopathologic Evaluation and Scoring of Viral Lung Infection JO: Methods Mol Biol http://www.kidney.de/pget.php?&tw=1&pmid=31883098 #FOAvip Emergent coronaviruses such as MERS-CoV and SARS-CoV can cause significant morbidity and mortality in infected individuals. Lung infection is a common clinical feature and contributes to disease severity as well as viral transmission. Animal models are often required to study viral infections and therapies, especially during an initial outbreak. Histopathology studies allow for identification of lesions and affected cell types to better understand viral pathogenesis and clarify effective therapies. Use of immunostaining allows detection of presumed viral receptors and viral tropism for cells can be evaluated to correlate with lesions. In the lung, lesions and immunostaining can be qualitatively described to define the cell types, microanatomic location, and type of changes seen. These features are important and necessary, but this approach can have limitations when comparing treatment groups. Semiquantitative and quantitative tissue scores are more rigorous as these provide the ability to statistically compare groups and increase the reproducibility and rigor of the study. This review describes principles, approaches, and resources that can be useful to evaluate coronavirus lung infection, focusing on MER-CoV infection as the principal example. Twit Text FOAVip Histopathologic Evaluation and Scoring of Viral Lung Infection ????Methods Mol Biol http://www.kidney.de/pget.php?&tw=1&pmid=31883098 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=31883098 #FOAvip English Wikipedia <ref>{{Cite pmid|31883098}}</ref> Histopathologic Evaluation and Scoring of Viral Lung Infection #MMPMID31883098 Meyerholz DK; Beck AP Methods Mol Biol 2020[]; 2099 (ä): 205-220 PMID31883098show ga Emergent coronaviruses such as MERS-CoV and SARS-CoV can cause significant morbidity and mortality in infected individuals. Lung infection is a common clinical feature and contributes to disease severity as well as viral transmission. Animal models are often required to study viral infections and therapies, especially during an initial outbreak. Histopathology studies allow for identification of lesions and affected cell types to better understand viral pathogenesis and clarify effective therapies. Use of immunostaining allows detection of presumed viral receptors and viral tropism for cells can be evaluated to correlate with lesions. In the lung, lesions and immunostaining can be qualitatively described to define the cell types, microanatomic location, and type of changes seen. These features are important and necessary, but this approach can have limitations when comparing treatment groups. Semiquantitative and quantitative tissue scores are more rigorous as these provide the ability to statistically compare groups and increase the reproducibility and rigor of the study. This review describes principles, approaches, and resources that can be useful to evaluate coronavirus lung infection, focusing on MER-CoV infection as the principal example. |*Viral Tropism[MESH] |Animals[MESH] |Coronavirus Infections/*pathology/virology[MESH] |Humans[MESH] |Lung/pathology/virology[MESH] |Mice[MESH] |Middle East Respiratory Syndrome Coronavirus/*physiology[MESH] |Reproducibility of Results[MESH]Histopathologic Evaluation and Scoring of Viral Lung Infection (epmc).pdf DeepDyve Pubget Overpricing