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10.1111/exd.14068 http://scihub22266oqcxt.onion/10.1111/exd.14068 31845391!7028117!31845391     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Exp+Dermatol 2020 ; 29 (2): 136-148 Nephropedia Template TP {{tp|p=31845391|t=2020. The importance of caveolins and caveolae to dermatology: Lessons from the caves and beyond |pdf=|usr=}}{{31845391}} gab.com Text The importance of caveolins and caveolae to dermatology: Lessons from the caves and beyond JO: Exp Dermatol http://www.kidney.de/pget.php?&tw=1&pmid=31845391 #FOAvip Caveolae are flask-shaped invaginations of the cell membrane rich in cholesterol and sphingomyelin, with caveolin proteins acting as their primary structural components that allow compartmentalization and orchestration of various signalling molecules. In this review, we discuss how pleiotropic functions of caveolin-1 (Cav1) and its intricate roles in numerous cellular functions including lipid trafficking, signalling, cell migration and proliferation, as well as cellular senescence, infection and inflammation, are integral for normal development and functioning of skin and its appendages. We then examine how disruption of the homeostatic levels of Cav1 can lead to development of various cutaneous pathophysiologies including skin cancers, cutaneous fibroses, psoriasis, alopecia, age-related changes in skin and aberrant wound healing and propose how levels of Cav1 may have theragnostic value in skin physiology/pathophysiology. Twit Text FOAVip The importance of caveolins and caveolae to dermatology: Lessons from the caves and beyond ????Exp Dermatol http://www.kidney.de/pget.php?&tw=1&pmid=31845391 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=31845391 #FOAvip English Wikipedia <ref>{{Cite pmid|31845391}}</ref> The importance of caveolins and caveolae to dermatology: Lessons from the caves and beyond #MMPMID31845391 Egger AN; Rajabiestarabadi A; Williams NM; Resnik SR; Fox JD; Wong LL; Jozic I Exp Dermatol 2020[Feb]; 29 (2): 136-148 PMID31845391show ga Caveolae are flask-shaped invaginations of the cell membrane rich in cholesterol and sphingomyelin, with caveolin proteins acting as their primary structural components that allow compartmentalization and orchestration of various signalling molecules. In this review, we discuss how pleiotropic functions of caveolin-1 (Cav1) and its intricate roles in numerous cellular functions including lipid trafficking, signalling, cell migration and proliferation, as well as cellular senescence, infection and inflammation, are integral for normal development and functioning of skin and its appendages. We then examine how disruption of the homeostatic levels of Cav1 can lead to development of various cutaneous pathophysiologies including skin cancers, cutaneous fibroses, psoriasis, alopecia, age-related changes in skin and aberrant wound healing and propose how levels of Cav1 may have theragnostic value in skin physiology/pathophysiology. |*Skin Physiological Phenomena[MESH] |Bacterial Infections/metabolism[MESH] |Caveolae/*physiology[MESH] |Caveolin 1/*metabolism[MESH] |Cell Movement[MESH] |Cell Proliferation[MESH] |Cellular Senescence[MESH] |Fibrosis/metabolism[MESH] |Hair/metabolism[MESH] |Humans[MESH] |Inflammation/metabolism[MESH] |Lipid Metabolism[MESH] |Psoriasis/metabolism[MESH] |Signal Transduction[MESH] |Skin Neoplasms/*metabolism[MESH] |Skin/*metabolism/pathology[MESH]The importance of caveolins and caveolae to dermatology: Lessons from (epmc).pdf DeepDyve Pubget Overpricing