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10.1556/004.2019.048

http://scihub22266oqcxt.onion/10.1556/004.2019.048
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31842595!ä!31842595

suck abstract from ncbi


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pmid31842595      Acta+Vet+Hung 2019 ; 67 (4): 489-498
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  • Antimicrobial susceptibility of Pasteurella multocida isolated from sheep and pigs in Spain - Short communication #MMPMID31842595
  • Cid D; Fernandez-Garayzabal JF; Pinto C; Dominguez L; Vela AI
  • Acta Vet Hung 2019[Dec]; 67 (4): 489-498 PMID31842595show ga
  • Pasteurella multocida is responsible for economically important diseases in sheep and pigs. Antimicrobial susceptibility studies are essential for initiating rational and effective empirical therapy of P. multocida infections. In this study we investigated the antimicrobial susceptibility to 18 antimicrobial agents of 156 clinical isolates of P. multocida from sheep (n = 87) and pigs (n = 69) using the microdilution method. Both sheep and pig isolates exhibited low levels of resistance ( 15% up to 50%) to oxytetracycline, tilmicosin, and tiamulin, and very high resistance rates (> 50%) to tylosin tartrate, clindamycin, and sulphadimethoxine. However, sheep isolates exhibited significantly lower percentages of resistance and lower MIC(90) values (P < 0.05) than pig isolates for most of the antimicrobials tested. In addition, sheep isolates exhibited also significantly lower phenotypic antimicrobial resistance diversity (8 resistotypes vs. 30 resistotypes). LAC-LIN-SUL-MAC was the resistotype most frequently detected in sheep (39.1%) and LIN-SUL-MAC in pig isolates (26.1%). The differences in susceptibility patterns could be influenced by the lower use of antimicrobials in the small ruminant industry compared with the pig farming industry.
  • |Animals[MESH]
  • |Anti-Bacterial Agents/*pharmacology[MESH]
  • |Microbial Sensitivity Tests/veterinary[MESH]
  • |Pasteurella multocida/*drug effects/genetics[MESH]
  • |Sheep, Domestic/*microbiology[MESH]
  • |Spain[MESH]


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