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10.3389/fphys.2019.01454 http://scihub22266oqcxt.onion/10.3389/fphys.2019.01454 31827445!6892402!31827445     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=31827445&cmd=llinks): Failed to open stream: HTTP request failed! 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Age and Muscle Function Are More Closely Associated With Intracellular Magnesium, as Assessed by (31)P Magnetic Resonance Spectroscopy, Than With Serum Magnesium |pdf=|usr=}}{{31827445}} gab.com Text Age and Muscle Function Are More Closely Associated With Intracellular Magnesium, as Assessed by (31)P Magnetic Resonance Spectroscopy, Than With Serum Magnesium JO: Front Physiol http://www.kidney.de/pget.php?&tw=1&pmid=31827445 #FOAvip Total serum magnesium is a common clinical measurement for assessing magnesium status; however, magnesium in blood represents less than 1% of the body's total magnesium content. We measured intramuscular ionized magnesium by phosphorus magnetic resonance spectroscopy ((31)P-MRS) and tested the hypothesis that this measure better correlates with skeletal muscle function and captures more closely the effect of aging than the traditional measure of total serum magnesium. Data were collected from 441 participants (age 24-98 years) in the Baltimore Longitudinal Study of Aging (BLSA), a study of normative aging that encompasses a broad age range. Results showed that intramuscular ionized magnesium was negatively associated with age (beta = -0.29, p < 0.001, R (2) = 0.08) and positively associated with knee-extension strength (beta = 0.31, p < 0.001, and R (2) = 0.1 in women; and beta = 0.2, p = 0.003, and R (2) = 0.04 in men), while total serum magnesium showed no association with age or strength (p = 0.27 and 0.1, respectively). Intramuscular ionized magnesium was significantly lower in women that in men (p < 0.001), perhaps due to chronic latent Mg deficiency in women that is not otherwise detected by serum magnesium levels. Based on these findings, we suggest that intramuscular ionized magnesium from (31)P-MRS is a better clinical measure of magnesium status than total serum magnesium, and could be measured when muscle weakness of unidentified etiology is detected. It may also be used to monitor the effectiveness of oral magnesium interventions, including supplementation. Twit Text FOAVip Age and Muscle Function Are More Closely Associated With Intracellular Magnesium, as Assessed by (31)P Magnetic Resonance Spectroscopy, Than With Serum Magnesium ????Front Physiol http://www.kidney.de/pget.php?&tw=1&pmid=31827445 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=31827445 #FOAvip English Wikipedia <ref>{{Cite pmid|31827445}}</ref> Age and Muscle Function Are More Closely Associated With Intracellular Magnesium, as Assessed by (31)P Magnetic Resonance Spectroscopy, Than With Serum Magnesium #MMPMID31827445 Cameron D; Welch AA; Adelnia F; Bergeron CM; Reiter DA; Dominguez LJ; Brennan NA; Fishbein KW; Spencer RG; Ferrucci L Front Physiol 2019[]; 10 (ä): 1454 PMID31827445show ga Total serum magnesium is a common clinical measurement for assessing magnesium status; however, magnesium in blood represents less than 1% of the body's total magnesium content. We measured intramuscular ionized magnesium by phosphorus magnetic resonance spectroscopy ((31)P-MRS) and tested the hypothesis that this measure better correlates with skeletal muscle function and captures more closely the effect of aging than the traditional measure of total serum magnesium. Data were collected from 441 participants (age 24-98 years) in the Baltimore Longitudinal Study of Aging (BLSA), a study of normative aging that encompasses a broad age range. Results showed that intramuscular ionized magnesium was negatively associated with age (beta = -0.29, p < 0.001, R (2) = 0.08) and positively associated with knee-extension strength (beta = 0.31, p < 0.001, and R (2) = 0.1 in women; and beta = 0.2, p = 0.003, and R (2) = 0.04 in men), while total serum magnesium showed no association with age or strength (p = 0.27 and 0.1, respectively). Intramuscular ionized magnesium was significantly lower in women that in men (p < 0.001), perhaps due to chronic latent Mg deficiency in women that is not otherwise detected by serum magnesium levels. Based on these findings, we suggest that intramuscular ionized magnesium from (31)P-MRS is a better clinical measure of magnesium status than total serum magnesium, and could be measured when muscle weakness of unidentified etiology is detected. It may also be used to monitor the effectiveness of oral magnesium interventions, including supplementation. äAge and Muscle Function Are More Closely Associated With Intracellular(epmc).pdf DeepDyve Pubget Overpricing