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10.1007/s00018-019-03401-0 http://scihub22266oqcxt.onion/10.1007/s00018-019-03401-0 31807815!7275011!31807815     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=31807815&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       Cell+Mol+Life+Sci 2020 ; 77 (12): 2257-2273 Nephropedia Template TP {{tp|p=31807815|t=2020. Stem cell-derived kidney organoids: engineering the vasculature |pdf=|usr=}}{{31807815}} gab.com Text Stem cell-derived kidney organoids: engineering the vasculature JO: Cell Mol Life Sci http://www.kidney.de/pget.php?&tw=1&pmid=31807815 #FOAvip Kidney organoids can be generated from human pluripotent stem cells (PSCs) using protocols that resemble the embryonic development of the kidney. The renal structures thus generated offer great potential for disease modeling, drug screening, and possibly future therapeutic application. At the same time, use of these PSC-derived organoids is hampered by lack of maturation and off-target differentiation. Here, we review the main protocols for the generation of kidney organoids from human-induced PSCs, discussing their advantages and limitations. In particular, we will focus on the vascularization of the kidney organoids, which appears to be one of the critical factors to achieve maturation and functionality of the organoids. Twit Text FOAVip Stem cell-derived kidney organoids: engineering the vasculature ????Cell Mol Life Sci http://www.kidney.de/pget.php?&tw=1&pmid=31807815 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=31807815 #FOAvip English Wikipedia <ref>{{Cite pmid|31807815}}</ref> Stem cell-derived kidney organoids: engineering the vasculature #MMPMID31807815 Koning M; van den Berg CW; Rabelink TJ Cell Mol Life Sci 2020[Jun]; 77 (12): 2257-2273 PMID31807815show ga Kidney organoids can be generated from human pluripotent stem cells (PSCs) using protocols that resemble the embryonic development of the kidney. The renal structures thus generated offer great potential for disease modeling, drug screening, and possibly future therapeutic application. At the same time, use of these PSC-derived organoids is hampered by lack of maturation and off-target differentiation. Here, we review the main protocols for the generation of kidney organoids from human-induced PSCs, discussing their advantages and limitations. In particular, we will focus on the vascularization of the kidney organoids, which appears to be one of the critical factors to achieve maturation and functionality of the organoids. |Animals[MESH] |Cell Culture Techniques/methods[MESH] |Cell Differentiation/physiology[MESH] |Humans[MESH] |Kidney/*cytology[MESH] |Organoids/*cytology[MESH]Stem cell-derived kidney organoids: engineering the vasculature (epmc).pdf DeepDyve Pubget Overpricing