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10.1093/jas/skz358

http://scihub22266oqcxt.onion/10.1093/jas/skz358
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suck abstract from ncbi


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pmid31758795      J+Anim+Sci 2020 ; 98 (1): ä
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  • Effect of dietary medium-chain fatty acids on nursery pig growth performance, fecal microbial composition, and mitigation properties against porcine epidemic diarrhea virus following storage #MMPMID31758795
  • Gebhardt JT; Thomson KA; Woodworth JC; Dritz SS; Tokach MD; DeRouchey JM; Goodband RD; Jones CK; Cochrane RA; Niederwerder MC; Fernando S; Abbas W; Burkey TE
  • J Anim Sci 2020[Jan]; 98 (1): ä PMID31758795show ga
  • An experiment was conducted to evaluate the effect of dietary medium-chain fatty acid (MCFA) addition on nursery pig growth performance, fecal microbial composition, and mitigation of porcine epidemic diarrhea virus (PEDV) following storage. A total of 360 pigs (DNA 400 x 200, Columbus, NE; initially 6.7 +/- 0.07 kg) were randomized to pens (5 pigs per pen) on the day of weaning (approximately 20 d of age), allowed a 6-d acclimation, blocked by BW, and randomized to dietary treatment (9 pens per treatment). All MCFA (Sigma-Aldrich, St. Louis, MO) were guaranteed >/=98% purity, including hexanoic (C6:0), octanoic (C8:0), and decanoic (C10:0) acids. Treatment diets were formulated in 2 phases (7 to 11 and 11 to 23 kg BW) and formulated to meet or exceed NRC requirement estimates. Treatments (n = 8) were a dose response including 0%, 0.25%, 0.5%, 1.0%, and 1.5% added MCFA blend (1:1:1 ratio C6:0, C8:0, and C10:0), as well as treatments with individual additions of 0.5% C6:0, C8:0, or C10:0. Fecal samples were collected from pigs fed control and 1.5% MCFA blend diets on days 0 and 14 and analyzed using 16s rDNA sequencing. Following feed manufacture, feed was stored in bags at barn temperature and humidity for 40 d before laboratory inoculation with PEDV. Subsamples of retained feed were inoculated with PEDV to achieve a titer of 104 TCID50/g and separate sample bottles were analyzed on 0 and 3 d post-inoculation (dpi). Overall, ADG and ADFI were increased (linear, P
  • |Animal Feed/*analysis[MESH]
  • |Animals[MESH]
  • |Coronavirus Infections/prevention & control/*veterinary/virology[MESH]
  • |Diet/veterinary[MESH]
  • |Fatty Acids/*pharmacology[MESH]
  • |Feces/microbiology[MESH]
  • |Female[MESH]
  • |Gastrointestinal Microbiome/*drug effects[MESH]
  • |Male[MESH]
  • |Porcine epidemic diarrhea virus/*drug effects[MESH]
  • |Swine[MESH]
  • |Swine Diseases/*prevention & control/virology[MESH]


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