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10.1111/tbed.13412 http://scihub22266oqcxt.onion/10.1111/tbed.13412 31682070!7138078!31682070     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\31682070.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Transbound+Emerg+Dis 2020 ; 67 (2): 884-893 Nephropedia Template TP {{tp|p=31682070|t=2020. Emerging lethal infectious bronchitis coronavirus variants with multiorgan tropism |pdf=|usr=}}{{31682070}} gab.com Text Emerging lethal infectious bronchitis coronavirus variants with multiorgan tropism JO: Transbound Emerg Dis http://www.kidney.de/pget.php?&tw=1&pmid=31682070 #FOAvip Infectious bronchitis virus (IBV) causes respiratory diseases in chickens and poses an economic threat to the poultry industry worldwide. Despite vaccine use, there have been field outbreaks of IBV in Taiwan. This study aimed to characterize the emerging IBV variants circulating in Taiwan. The analysis of the structural protein genes showed that these variants emerged through frequent recombination events among Taiwan strains, China strains, Japan strains and vaccine strains. Cross-neutralization tests revealed that two of the variants exhibited novel serotypes. Clinicopathological assessment showed that two of the variants caused high fatality rates of 67% and 20% in one-day-old SPF chicks, and all the variants possessed multiorgan tropisms, including trachea, proventriculus and urogenital tissues. Furthermore, the commercial live-attenuated Mass-type vaccine conferred poor protection against these variants. This study identified novel genotypes, serotypes and pathotypes of emerging IBV variants circulating in Taiwan. There is an urgent need for effective countermeasures against these variant strains. Twit Text FOAVip Emerging lethal infectious bronchitis coronavirus variants with multiorgan tropism ????Transbound Emerg Dis http://www.kidney.de/pget.php?&tw=1&pmid=31682070 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=31682070 #FOAvip English Wikipedia <ref>{{Cite pmid|31682070}}</ref> Emerging lethal infectious bronchitis coronavirus variants with multiorgan tropism #MMPMID31682070 Li YT; Chen TC; Lin SY; Mase M; Murakami S; Horimoto T; Chen HW Transbound Emerg Dis 2020[Mar]; 67 (2): 884-893 PMID31682070show ga Infectious bronchitis virus (IBV) causes respiratory diseases in chickens and poses an economic threat to the poultry industry worldwide. Despite vaccine use, there have been field outbreaks of IBV in Taiwan. This study aimed to characterize the emerging IBV variants circulating in Taiwan. The analysis of the structural protein genes showed that these variants emerged through frequent recombination events among Taiwan strains, China strains, Japan strains and vaccine strains. Cross-neutralization tests revealed that two of the variants exhibited novel serotypes. Clinicopathological assessment showed that two of the variants caused high fatality rates of 67% and 20% in one-day-old SPF chicks, and all the variants possessed multiorgan tropisms, including trachea, proventriculus and urogenital tissues. Furthermore, the commercial live-attenuated Mass-type vaccine conferred poor protection against these variants. This study identified novel genotypes, serotypes and pathotypes of emerging IBV variants circulating in Taiwan. There is an urgent need for effective countermeasures against these variant strains. |Animals[MESH] |Bronchitis/*veterinary/virology[MESH] |Chickens/*virology[MESH] |Coronavirus Infections/epidemiology/*veterinary/virology[MESH] |Disease Outbreaks/*veterinary[MESH] |Female[MESH] |Genetic Variation[MESH] |Infectious bronchitis virus/*genetics/immunology/physiology[MESH] |Poultry Diseases/epidemiology/*virology[MESH] |Proventriculus/virology[MESH] |Specific Pathogen-Free Organisms[MESH] |Taiwan/epidemiology[MESH] |Trachea/virology[MESH]Emerging lethal infectious bronchitis coronavirus variants with multio(epmc).pdf DeepDyve Pubget Overpricing