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Deprecated: Implicit conversion from float 269.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Influenza+Other+Respir+Viruses 2020 ; 14 (1): 46-54 Nephropedia Template TP
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The burden and clinical manifestation of hospitalized influenza among different pediatric age-groups in the tropics #MMPMID31608598
Chong CY; Yung CF; Gan C; Thio ST; Tan NW; Tee NW; Lin C; Lin RT; Thoon KC
Influenza Other Respir Viruses 2020[Jan]; 14 (1): 46-54 PMID31608598show ga
INTRODUCTION: In tropical Singapore, influenza occurs all year-round. This study of influenza-confirmed hospitalized pediatric patients compared clinical characteristics and complications by age-group and differences between influenza A and B. METHODS: This was a retrospective study of pediatric inpatients from January 2013 to December 2014. Patients were grouped into: <6 months, 6 months to <5 years, 5- to <10-year and >/=10 years. Complications were classified into neurologic, pulmonary, and other. We also calculated the incidence of hospitalized influenza cases per 100 000 age-related population. RESULTS: There were a total of 1272 patients with a median age of 37 months. The highest hospitalization rates were in the <6 months age-group. Majority (75.2%) had no comorbidity; 25.6% had complications: neurologic 11.9%, pulmonary 9.6%, other 4.1%. Patients with other complications were older, male, and had the highest influenza B rates and the longest length of stay. Influenza A comprised 76.9% of cases and had higher complication rates especially neurologic, compared to influenza B. Influenza B patients were older and were more likely to develop other complications. The 6-month to <5-year-age-group had the highest complication rate (30.6%), especially neurologic. However, >/=10 years old had the highest other complications, ICU/ high-dependency admissions and influenza B Victoria rates. CONCLUSIONS: Infants <6 months had the highest hospitalization rates for influenza. The 6-month to <5-year-age-group had the highest complication rate especially neurologic. Influenza A patients were younger, had higher seizure rates and complications compared to influenza B.