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10.1038/s41429-019-0234-4 http://scihub22266oqcxt.onion/10.1038/s41429-019-0234-4 31534199!ä!31534199 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Antibiot+(Tokyo) 2019 ; 72 (12): 981-985 Nephropedia Template TP {{tp|p=31534199|t=2019. Antiviral effect of sinefungin on in vitro growth of feline herpesvirus type 1 |pdf=|usr=}}{{31534199}} gab.com Text Antiviral effect of sinefungin on in vitro growth of feline herpesvirus type 1 JO: J Antibiot (Tokyo) http://www.kidney.de/pget.php?&tw=1&pmid=31534199 #FOAvip Feline herpesvirus type 1 (FHV-1) causes a potentially fatal disease in cats. Through the use of virus inhibition and cytotoxicity assays, sinefungin, a nucleoside antibiotic, was assessed for its potential to inhibit the growth of FHV-1. Sinefungin inhibited in vitro growth of FHV-1 most significantly over other animal viruses, such as feline infectious peritonitis virus, equine herpesvirus, pseudorabies virus and feline calicivirus. Our results revealed that sinefungin specifically suppressed the replication of FHV-1 after its adsorption to the host feline kidney cells in a dose-dependent manner without obvious cytotoxicity to the host cells. This antibiotic can potentially offer a highly effective treatment for animals infected with FHV-1, providing alternative medication to currently available antiviral therapies. Twit Text FOAVip Antiviral effect of sinefungin on in vitro growth of feline herpesvirus type 1 ????J Antibiot (Tokyo) http://www.kidney.de/pget.php?&tw=1&pmid=31534199 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=31534199 #FOAvip English Wikipedia <ref>{{Cite pmid|31534199}}</ref> Antiviral effect of sinefungin on in vitro growth of feline herpesvirus type 1 #MMPMID31534199 Kuroda Y; Yamagata H; Nemoto M; Inagaki K; Tamura T; Maeda K J Antibiot (Tokyo) 2019[Dec]; 72 (12): 981-985 PMID31534199show ga Feline herpesvirus type 1 (FHV-1) causes a potentially fatal disease in cats. Through the use of virus inhibition and cytotoxicity assays, sinefungin, a nucleoside antibiotic, was assessed for its potential to inhibit the growth of FHV-1. Sinefungin inhibited in vitro growth of FHV-1 most significantly over other animal viruses, such as feline infectious peritonitis virus, equine herpesvirus, pseudorabies virus and feline calicivirus. Our results revealed that sinefungin specifically suppressed the replication of FHV-1 after its adsorption to the host feline kidney cells in a dose-dependent manner without obvious cytotoxicity to the host cells. This antibiotic can potentially offer a highly effective treatment for animals infected with FHV-1, providing alternative medication to currently available antiviral therapies. |Adenosine/*analogs & derivatives/pharmacology/toxicity[MESH] |Animals[MESH] |Antiviral Agents/*pharmacology/toxicity[MESH] |Calicivirus, Feline/drug effects[MESH] |Cat Diseases/drug therapy[MESH] |Cats[MESH] |Cell Line[MESH] |Coronavirus, Feline/drug effects[MESH] |Dose-Response Relationship, Drug[MESH] |Herpesviridae Infections/drug therapy/veterinary[MESH] |Herpesvirus 1, Equid/drug effects[MESH] |Herpesvirus 1, Suid/drug effects[MESH] |Horses[MESH] |Kidney/cytology/virology[MESH] |Toxicity Tests[MESH]Antiviral effect of sinefungin on in vitro growth of feline herpesviru(epmc).pdf DeepDyve Pubget Overpricing