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10.1016/j.virol.2019.08.031 http://scihub22266oqcxt.onion/10.1016/j.virol.2019.08.031 31505321!7112113!31505321     free     free     free       Virology 2019 ; 537 (ä): 198-207 Nephropedia Template TP {{tp|p=31505321|t=2019. Coronavirus genomic RNA packaging |pdf=|usr=}}{{31505321}} gab.com Text Coronavirus genomic RNA packaging JO: Virology http://www.kidney.de/pget.php?&tw=1&pmid=31505321 #FOAvip RNA viruses carry out selective packaging of their genomes in a variety of ways, many involving a genomic packaging signal. The first coronavirus packaging signal was discovered nearly thirty years ago, but how it functions remains incompletely understood. This review addresses the current state of knowledge of coronavirus genome packaging, which has mainly been studied in two prototype species, mouse hepatitis virus and transmissible gastroenteritis virus. Despite the progress that has been made in the mapping and characterization of some packaging signals, there is conflicting evidence as to whether the viral nucleocapsid protein or the membrane protein plays the primary role in packaging signal recognition. The different models for the mechanism of genomic RNA packaging that have been prompted by these competing views are described. Also discussed is the recent exciting discovery that selective coronavirus genome packaging is critical for in vivo evasion of the host innate immune response. Twit Text FOAVip Coronavirus genomic RNA packaging ????Virology http://www.kidney.de/pget.php?&tw=1&pmid=31505321 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=31505321 #FOAvip English Wikipedia <ref>{{Cite pmid|31505321}}</ref> Coronavirus genomic RNA packaging #MMPMID31505321 Masters PS Virology 2019[Nov]; 537 (ä): 198-207 PMID31505321show ga RNA viruses carry out selective packaging of their genomes in a variety of ways, many involving a genomic packaging signal. The first coronavirus packaging signal was discovered nearly thirty years ago, but how it functions remains incompletely understood. This review addresses the current state of knowledge of coronavirus genome packaging, which has mainly been studied in two prototype species, mouse hepatitis virus and transmissible gastroenteritis virus. Despite the progress that has been made in the mapping and characterization of some packaging signals, there is conflicting evidence as to whether the viral nucleocapsid protein or the membrane protein plays the primary role in packaging signal recognition. The different models for the mechanism of genomic RNA packaging that have been prompted by these competing views are described. Also discussed is the recent exciting discovery that selective coronavirus genome packaging is critical for in vivo evasion of the host innate immune response. |*Virus Assembly[MESH] |Models, Biological[MESH] |Murine hepatitis virus/*physiology[MESH] |Nucleocapsid Proteins/metabolism[MESH] |RNA, Viral/*metabolism[MESH] |Transmissible gastroenteritis virus/*physiology[MESH]Coronavirus genomic RNA packaging (epmc).pdf DeepDyve Pubget Overpricing