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10.1016/bs.ctm.2019.01.001 http://scihub22266oqcxt.onion/10.1016/bs.ctm.2019.01.001 31196609!6815098!31196609     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Curr+Top+Membr 2019 ; 83 (ä): 353-396 Nephropedia Template TP {{tp|p=31196609|t=2019. Ion channels and transporters in diabetic kidney disease |pdf=|usr=}}{{31196609}} gab.com Text Ion channels and transporters in diabetic kidney disease JO: Curr Top Membr http://www.kidney.de/pget.php?&tw=1&pmid=31196609 #FOAvip Type 1 and 2 diabetes mellitus are major medical epidemics affecting millions of patients worldwide. Diabetes mellitus is the leading cause of diabetic kidney disease (DKD), which is the most common cause of end-stage renal disease (ESRD). DKD is associated with significant changes in renal hemodynamics and electrolyte transport. Alterations in renal ion transport triggered by pathophysiological conditions in diabetes can exacerbate hypertension, accelerate renal injury, and are integral to the development of DKD. Renal ion transporters and electrolyte homeostasis play a fundamental role in functional changes and injury to the kidney during DKD. With the large number of ion transporters involved in DKD, understanding the roles of individual transporters as well as the complex cascades through which they interact is essential in the development of effective treatments for patients suffering from this disease. This chapter aims to gather current knowledge of the major renal ion transporters with altered expression and activity under diabetic conditions, and provide a comprehensive overview of their interactions and collective functions in DKD. Twit Text FOAVip Ion channels and transporters in diabetic kidney disease ????Curr Top Membr http://www.kidney.de/pget.php?&tw=1&pmid=31196609 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=31196609 #FOAvip English Wikipedia <ref>{{Cite pmid|31196609}}</ref> Ion channels and transporters in diabetic kidney disease #MMPMID31196609 Spires D; Manis AD; Staruschenko A Curr Top Membr 2019[]; 83 (ä): 353-396 PMID31196609show ga Type 1 and 2 diabetes mellitus are major medical epidemics affecting millions of patients worldwide. Diabetes mellitus is the leading cause of diabetic kidney disease (DKD), which is the most common cause of end-stage renal disease (ESRD). DKD is associated with significant changes in renal hemodynamics and electrolyte transport. Alterations in renal ion transport triggered by pathophysiological conditions in diabetes can exacerbate hypertension, accelerate renal injury, and are integral to the development of DKD. Renal ion transporters and electrolyte homeostasis play a fundamental role in functional changes and injury to the kidney during DKD. With the large number of ion transporters involved in DKD, understanding the roles of individual transporters as well as the complex cascades through which they interact is essential in the development of effective treatments for patients suffering from this disease. This chapter aims to gather current knowledge of the major renal ion transporters with altered expression and activity under diabetic conditions, and provide a comprehensive overview of their interactions and collective functions in DKD. |Animals[MESH] |Diabetic Nephropathies/*metabolism[MESH] |Humans[MESH]Ion channels and transporters in diabetic kidney disease (epmc).pdf DeepDyve Pubget Overpricing