
| 10.1016/j.jiph.2019.04.011
http://scihub22266oqcxt.onion/10.1016/j.jiph.2019.04.011
 31056437!7102841!31056437
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J+Infect+Public+Health 2020 ; 13 (3): 418-422 Nephropedia Template TP
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MERS-CoV infection among healthcare workers and risk factors for death: Retrospective analysis of all laboratory-confirmed cases reported to WHO from 2012 to 2 June 2018 #MMPMID31056437Elkholy AA; Grant R; Assiri A; Elhakim M; Malik MR; Van Kerkhove MDJ Infect Public Health 2020[Mar]; 13 (3): 418-422 PMID31056437show ga
BACKGROUND: Approximately half of the reported laboratory-confirmed infections of Middle East respiratory syndrome coronavirus (MERS-CoV) have occurred in healthcare settings, and healthcare workers constitute over one third of all secondary infections. This study aimed to describe secondary cases of MERS-CoV infection among healthcare workers and to identify risk factors for death. METHODS: A retrospective analysis was conducted on epidemiological data of laboratory-confirmed MERS-CoV cases reported to the World Health Organization from September 2012 to 2 June 2018. We compared all secondary cases among healthcare workers with secondary cases among non-healthcare workers. Multivariable logistic regression identified risk factors for death. RESULTS: Of the 2223 laboratory-confirmed MERS-CoV cases reported to WHO, 415 were healthcare workers and 1783 were non-healthcare workers. Compared with non-healthcare workers cases, healthcare workers cases were younger (P < 0.001), more likely to be female (P < 0.001), non-nationals (P < 0.001) and asymptomatic (P < 0.001), and have fewer comorbidities (P < 0.001) and higher rates of survival (P < 0.001). Year of infection (2013-2018) and having no comorbidities were independent protective factors against death among secondary healthcare workers cases. CONCLUSION: Being able to protect healthcare workers from high threat respiratory pathogens, such as MERS-CoV is important for being able to reduce secondary transmission of MERS-CoV in healthcare-associated outbreaks. By extension, reducing infection in healthcare workers improves continuity of care for all patients within healthcare facilities.|*Health Personnel[MESH]|*Middle East Respiratory Syndrome Coronavirus[MESH]|Adult[MESH]|Coronavirus Infections/*epidemiology/mortality/*transmission[MESH]|Cross Infection/epidemiology/transmission[MESH]|Female[MESH]|Humans[MESH]|Infectious Disease Transmission, Patient-to-Professional/prevention & control[MESH]|Laboratories[MESH]|Male[MESH]|Middle Aged[MESH]|Retrospective Studies[MESH]|Risk Factors[MESH]
  
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