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10.3389/fimmu.2019.00772 http://scihub22266oqcxt.onion/10.3389/fimmu.2019.00772 31037070!6476281!31037070     free     free     free       Front+Immunol 2019 ; 10 (?): 772 Nephropedia Template TP {{tp|p=31037070|t=2019. Innate Immune Cells Contribution to Systemic Lupus Erythematosus |pdf=|usr=}}{{31037070}} gab.com Text Innate Immune Cells Contribution to Systemic Lupus Erythematosus JO: Front Immunol http://www.kidney.de/pget.php?&tw=1&pmid=31037070 #FOAvip Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by the presence of autoantibodies against nuclear antigens, immune complex deposition, and tissue damage in the kidneys, skin, heart and lung. Because of the pathogenic role of antinuclear antibodies and autoreactive T cells in SLE, extensive efforts have been made to demonstrate how B cells act as antibody-producing or as antigen-presenting cells that can prime autoreactive T cell activation. With the discovery of new innate immune cells and inflammatory mediators, innate immunity is emerging as a key player in disease pathologies. Recent work over the last decade has highlighted the importance of innate immune cells and molecules in promoting and potentiating SLE. In this review, we discuss recent evidence of the involvement of different innate immune cells and pathways in the pathogenesis of SLE. We also discuss new therapeutics targets directed against innate immune components as potential novel therapies in SLE. Twit Text FOAVip Innate Immune Cells Contribution to Systemic Lupus Erythematosus ????Front Immunol http://www.kidney.de/pget.php?&tw=1&pmid=31037070 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=31037070 #FOAvip English Wikipedia <ref>{{Cite pmid|31037070}}</ref> Innate Immune Cells Contribution to Systemic Lupus Erythematosus #MMPMID31037070 Herrada AA; Escobedo N; Iruretagoyena M; Valenzuela RA; Burgos PI; Cuitino L; Llanos C Front Immunol 2019[]; 10 (?): 772 PMID31037070show ga Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by the presence of autoantibodies against nuclear antigens, immune complex deposition, and tissue damage in the kidneys, skin, heart and lung. Because of the pathogenic role of antinuclear antibodies and autoreactive T cells in SLE, extensive efforts have been made to demonstrate how B cells act as antibody-producing or as antigen-presenting cells that can prime autoreactive T cell activation. With the discovery of new innate immune cells and inflammatory mediators, innate immunity is emerging as a key player in disease pathologies. Recent work over the last decade has highlighted the importance of innate immune cells and molecules in promoting and potentiating SLE. In this review, we discuss recent evidence of the involvement of different innate immune cells and pathways in the pathogenesis of SLE. We also discuss new therapeutics targets directed against innate immune components as potential novel therapies in SLE. |Animals[MESH] |Humans[MESH] |Immunity, Innate/*immunology[MESH]Innate Immune Cells Contribution to Systemic Lupus Erythematosus (epmc).pdf DeepDyve Pubget Overpricing