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10.1172/JCI124611 http://scihub22266oqcxt.onion/10.1172/JCI124611 30855278!6436902!30855278     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=30855278&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       J+Clin+Invest 2019 ; 129 (4): 1493-1503 Nephropedia Template TP {{tp|p=30855278|t=2019. Precision medicine and phenotypes, endotypes, genotypes, regiotypes, and theratypes of allergic diseases |pdf=|usr=}}{{30855278}} gab.com Text Precision medicine and phenotypes, endotypes, genotypes, regiotypes, and theratypes of allergic diseases JO: J Clin Invest http://www.kidney.de/pget.php?&tw=1&pmid=30855278 #FOAvip A rapidly developing paradigm for modern health care is a proactive and individualized response to patients' symptoms, combining precision diagnosis and personalized treatment. Precision medicine is becoming an overarching medical discipline that will require a better understanding of biomarkers, phenotypes, endotypes, genotypes, regiotypes, and theratypes of diseases. The 100-year-old personalized allergen-specific management of allergic diseases has particularly contributed to early awareness in precision medicine. Polyomics, big data, and systems biology have demonstrated a profound complexity and dynamic variability in allergic disease between individuals, as well as between regions. Escalating health care costs together with questionable efficacy of the current management of allergic diseases facilitated the emergence of the endotype-driven approach. We describe here a precision medicine approach that stratifies patients based on disease mechanisms to optimize management of allergic diseases. Twit Text FOAVip Precision medicine and phenotypes, endotypes, genotypes, regiotypes, and theratypes of allergic diseases ????J Clin Invest http://www.kidney.de/pget.php?&tw=1&pmid=30855278 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=30855278 #FOAvip English Wikipedia <ref>{{Cite pmid|30855278}}</ref> Precision medicine and phenotypes, endotypes, genotypes, regiotypes, and theratypes of allergic diseases #MMPMID30855278 Agache I; Akdis CA J Clin Invest 2019[Mar]; 129 (4): 1493-1503 PMID30855278show ga A rapidly developing paradigm for modern health care is a proactive and individualized response to patients' symptoms, combining precision diagnosis and personalized treatment. Precision medicine is becoming an overarching medical discipline that will require a better understanding of biomarkers, phenotypes, endotypes, genotypes, regiotypes, and theratypes of diseases. The 100-year-old personalized allergen-specific management of allergic diseases has particularly contributed to early awareness in precision medicine. Polyomics, big data, and systems biology have demonstrated a profound complexity and dynamic variability in allergic disease between individuals, as well as between regions. Escalating health care costs together with questionable efficacy of the current management of allergic diseases facilitated the emergence of the endotype-driven approach. We describe here a precision medicine approach that stratifies patients based on disease mechanisms to optimize management of allergic diseases. |*Genotype[MESH] |*Hypersensitivity/genetics/immunology/pathology/therapy[MESH] |*Precision Medicine[MESH]Precision medicine and phenotypes, endotypes, genotypes, regiotypes, a(epmc).pdf DeepDyve Pubget Overpricing