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10.1111/aogs.13603

http://scihub22266oqcxt.onion/10.1111/aogs.13603
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30835813!ä!30835813

suck abstract from ncbi


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pmid30835813      Acta+Obstet+Gynecol+Scand 2019 ; 98 (9): 1157-1163
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  • Antibiotic treatment for patients with amniotic fluid "sludge" to prevent spontaneous preterm birth: A historically controlled observational study #MMPMID30835813
  • Hatanaka AR; Franca MS; Hamamoto TENK; Rolo LC; Mattar R; Moron AF
  • Acta Obstet Gynecol Scand 2019[Sep]; 98 (9): 1157-1163 PMID30835813show ga
  • INTRODUCTION: Amniotic fluid "sludge" has been associated with an increased rate of spontaneous preterm delivery before 35 weeks, a higher frequency of clinical and histologic chorioamnionitis in a high-risk population. Only one study evaluating the use of antibiotics in the presence of amniotic fluid "sludge" showed reduced rates of spontaneous preterm birth at <34 weeks. The objective of this study was to evaluate routine antibiotic treatment in the presence of amniotic fluid "sludge" for prevention of preterm delivery. MATERIAL AND METHODS: A historically controlled observational study was performed between October 2010 and January 2015, including a total of 86 pregnant women with singleton pregnancies and the presence of amniotic fluid "sludge" at ultrasound. Women admitted from October 2010 to September 2012 received no treatment with antibiotics, whereas those admitted from October 2012 to January 2015, received routinely clindamycin and first-generation cephalosporin. The groups were compared considering the incidence of spontaneous preterm delivery. The effect of antimicrobials was also compared in the subgroup of women at high risk for spontaneous preterm birth (ie, cervical length
  • |Adult[MESH]
  • |Amniotic Fluid/*diagnostic imaging[MESH]
  • |Anti-Bacterial Agents/*therapeutic use[MESH]
  • |Birth Weight[MESH]
  • |Chorioamnionitis/*drug therapy[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Obstetric Labor, Premature/*prevention & control[MESH]
  • |Pregnancy[MESH]
  • |Pregnancy Outcome[MESH]
  • |Premature Birth/*prevention & control[MESH]


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