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10.1136/jim-2018-000966 http://scihub22266oqcxt.onion/10.1136/jim-2018-000966 30826804!6660364!30826804     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Investig+Med 2019 ; 67 (6): 987-994 Nephropedia Template TP {{tp|p=30826804|t=2019. Low serum magnesium is associated with faster decline in kidney function: the Dallas Heart Study experience |pdf=|usr=}}{{30826804}} gab.com Text Low serum magnesium is associated with faster decline in kidney function: the Dallas Heart Study experience JO: J Investig Med http://www.kidney.de/pget.php?&tw=1&pmid=30826804 #FOAvip Hypomagnesemia associates with inflammation and risk of diabetes and hypertension, which may contribute to kidney function decline. We hypothesized that low serum magnesium (SMg) levels independently associate with a significant decline in estimated glomerular filtration rate (eGFR). We analyzed SMg levels in 2056 participants from the Dallas Heart Study, a longitudinal, population-based, multiethnic, cohort study involving residents of Dallas County, Texas, USA. The primary study outcome was the change in eGFR using multivariable linear regression models adjusted for demographics, anthropometric and biochemical parameters, medications, C reactive protein levels, prevalent hypertension and diabetes. During a median follow-up of 7.0 years (25th, 75th percentile: 6.5, 7.6), the median decrease in eGFR was -0.71 (25th, 75th percentile: -2.43, +0.68) mL/min/1.73 m(2) per year in the entire cohort. In a fully adjusted model, the lowest SMg quintile (</=1.9 mg/dL or </=0.8 mM) was associated with a -0.50 mL/min/1.73 m(2) per year drop in eGFR (95% CI -0.95 to -0.05; p=0.028) compared with the highest SMg quintile (>/=2.3 mg/dL or >/=1.0 mM). Every 0.2 mg/dL (0.08 mM) decrease in SMg was associated with an eGFR decline of -0.23 mL/min/1.73 m(2) per year (95% CI -0.38 to -0.08; p=0.003), a decline that was more pronounced in participants with prevalent diabetes compared with patients without diabetes (-0.51 vs -0.18 mL/min/1.73 m(2) per year, respectively). In conclusion, low SMg was independently associated with eGFR decline. Further studies are needed to determine whether Mg repletion can ameliorate inflammation, lower blood pressure and serum glucose and ultimately prevent or retard kidney function decline. Twit Text FOAVip Low serum magnesium is associated with faster decline in kidney function: the Dallas Heart Study experience ????J Investig Med http://www.kidney.de/pget.php?&tw=1&pmid=30826804 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=30826804 #FOAvip English Wikipedia <ref>{{Cite pmid|30826804}}</ref> Low serum magnesium is associated with faster decline in kidney function: the Dallas Heart Study experience #MMPMID30826804 Ferre S; Li X; Adams-Huet B; Maalouf NM; Sakhaee K; Toto RD; Moe OW; Neyra JA J Investig Med 2019[Aug]; 67 (6): 987-994 PMID30826804show ga Hypomagnesemia associates with inflammation and risk of diabetes and hypertension, which may contribute to kidney function decline. We hypothesized that low serum magnesium (SMg) levels independently associate with a significant decline in estimated glomerular filtration rate (eGFR). We analyzed SMg levels in 2056 participants from the Dallas Heart Study, a longitudinal, population-based, multiethnic, cohort study involving residents of Dallas County, Texas, USA. The primary study outcome was the change in eGFR using multivariable linear regression models adjusted for demographics, anthropometric and biochemical parameters, medications, C reactive protein levels, prevalent hypertension and diabetes. During a median follow-up of 7.0 years (25th, 75th percentile: 6.5, 7.6), the median decrease in eGFR was -0.71 (25th, 75th percentile: -2.43, +0.68) mL/min/1.73 m(2) per year in the entire cohort. In a fully adjusted model, the lowest SMg quintile (/=2.3 mg/dL or >/=1.0 mM). Every 0.2 mg/dL (0.08 mM) decrease in SMg was associated with an eGFR decline of -0.23 mL/min/1.73 m(2) per year (95% CI -0.38 to -0.08; p=0.003), a decline that was more pronounced in participants with prevalent diabetes compared with patients without diabetes (-0.51 vs -0.18 mL/min/1.73 m(2) per year, respectively). In conclusion, low SMg was independently associated with eGFR decline. Further studies are needed to determine whether Mg repletion can ameliorate inflammation, lower blood pressure and serum glucose and ultimately prevent or retard kidney function decline. |Adult[MESH] |Aged[MESH] |Cohort Studies[MESH] |Diabetes Mellitus/epidemiology[MESH] |Female[MESH] |Glomerular Filtration Rate[MESH] |Humans[MESH] |Kidney/*physiopathology[MESH] |Linear Models[MESH] |Magnesium/*blood[MESH] |Male[MESH] |Middle Aged[MESH] |Multivariate Analysis[MESH]Low serum magnesium is associated with faster decline in kidney functi(epmc).pdf DeepDyve Pubget Overpricing