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Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Magnesium 1988 ; 7 (5-6): 281-9 Nephropedia Template TP
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Phagocytes and monokines: perspectives on metabolic regulation in sepsis #MMPMID3075244
Sacco NA; Filkins JP
Magnesium 1988[]; 7 (5-6): 281-9 PMID3075244show ga
The importance of monocytes and macrophages in antimicrobial host defense physiology has long been recognized. The mononuclear phagocyte system includes the precursor cells in bone marrow, or promonocytes, circulating peripheral blood monocytes, and the resident tissue macrophages of both fixed and free types. This review focuses on the pathophysiological role of the monokines, especially interleukin-1 in metabolic regulation during sepsis.