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10.1007/s00262-018-2277-y

http://scihub22266oqcxt.onion/10.1007/s00262-018-2277-y
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30569204!11028159!30569204
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suck abstract from ncbi

pmid30569204      Cancer+Immunol+Immunother 2019 ; 68 (4): 673-685
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  • MDSCs in infectious diseases: regulation, roles, and readjustment #MMPMID30569204
  • Dorhoi A; Glaria E; Garcia-Tellez T; Nieuwenhuizen NE; Zelinskyy G; Favier B; Singh A; Ehrchen J; Gujer C; Munz C; Saraiva M; Sohrabi Y; Sousa AE; Delputte P; Muller-Trutwin M; Valledor AF
  • Cancer Immunol Immunother 2019[Apr]; 68 (4): 673-685 PMID30569204show ga
  • Many pathogens, ranging from viruses to multicellular parasites, promote expansion of MDSCs, which are myeloid cells that exhibit immunosuppressive features. The roles of MDSCs in infection depend on the class and virulence mechanisms of the pathogen, the stage of the disease, and the pathology associated with the infection. This work compiles evidence supported by functional assays on the roles of different subsets of MDSCs in acute and chronic infections, including pathogen-associated malignancies, and discusses strategies to modulate MDSC dynamics to benefit the host.
  • |Acute Disease[MESH]
  • |Animals[MESH]
  • |Biomarkers[MESH]
  • |Chronic Disease[MESH]
  • |Communicable Diseases/drug therapy/*etiology/*metabolism[MESH]
  • |Disease Susceptibility[MESH]
  • |Host-Pathogen Interactions/immunology[MESH]
  • |Humans[MESH]
  • |Immunomodulation[MESH]
  • |Molecular Targeted Therapy[MESH]


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