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10.1515/hsz-2018-0271 http://scihub22266oqcxt.onion/10.1515/hsz-2018-0271 30504522!ä!30504522 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Biol+Chem 2019 ; 400 (5): 629-638 Nephropedia Template TP {{tp|p=30504522|t=2019. The comparative biochemistry of viruses and humans: an evolutionary path towards autoimmunity |pdf=|usr=}}{{30504522}} gab.com Text The comparative biochemistry of viruses and humans: an evolutionary path towards autoimmunity JO: Biol Chem http://www.kidney.de/pget.php?&tw=1&pmid=30504522 #FOAvip Analyses of the peptide sharing between five common human viruses (Borna disease virus, influenza A virus, measles virus, mumps virus and rubella virus) and the human proteome highlight a massive viral vs. human peptide overlap that is mathematically unexpected. Evolutionarily, the data underscore a strict relationship between viruses and the origin of eukaryotic cells. Indeed, according to the viral eukaryogenesis hypothesis and in light of the endosymbiotic theory, the first eukaryotic cell (our lineage) originated as a consortium consisting of an archaeal ancestor of the eukaryotic cytoplasm, a bacterial ancestor of the mitochondria and a viral ancestor of the nucleus. From a pathologic point of view, the peptide sequence similarity between viruses and humans may provide a molecular platform for autoimmune crossreactions during immune responses following viral infections/immunizations. Twit Text FOAVip The comparative biochemistry of viruses and humans: an evolutionary path towards autoimmunity ????Biol Chem http://www.kidney.de/pget.php?&tw=1&pmid=30504522 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=30504522 #FOAvip English Wikipedia <ref>{{Cite pmid|30504522}}</ref> The comparative biochemistry of viruses and humans: an evolutionary path towards autoimmunity #MMPMID30504522 Kanduc D Biol Chem 2019[Apr]; 400 (5): 629-638 PMID30504522show ga Analyses of the peptide sharing between five common human viruses (Borna disease virus, influenza A virus, measles virus, mumps virus and rubella virus) and the human proteome highlight a massive viral vs. human peptide overlap that is mathematically unexpected. Evolutionarily, the data underscore a strict relationship between viruses and the origin of eukaryotic cells. Indeed, according to the viral eukaryogenesis hypothesis and in light of the endosymbiotic theory, the first eukaryotic cell (our lineage) originated as a consortium consisting of an archaeal ancestor of the eukaryotic cytoplasm, a bacterial ancestor of the mitochondria and a viral ancestor of the nucleus. From a pathologic point of view, the peptide sequence similarity between viruses and humans may provide a molecular platform for autoimmune crossreactions during immune responses following viral infections/immunizations. |*Autoimmunity[MESH] |Amino Acid Sequence[MESH] |Borna disease virus/*immunology[MESH] |Humans[MESH] |Influenza A virus/*immunology[MESH] |Measles virus/*immunology[MESH] |Mumps virus/*immunology[MESH] |Peptides/*immunology[MESH]The comparative biochemistry of viruses and humans: an evolutionary pa(epmc).pdf DeepDyve Pubget Overpricing