Pinheiro SVB; Dias RF; Fabiano RCG; Araujo SA; Silva ACSE
J Bras Nefrol 2019[Apr]; 41 (2): 252-265 PMID30465590show ga
Involvement of the kidneys by lupus nephritis (LN) is one of the most severe clinical manifestations seen in individuals with systemic lupus erythematosus (SLE). LN is more frequent and severe in pediatric patients and has been associated with higher morbidity and mortality rates. This narrative review aimed to describe the general aspects of LN and its particularities when affecting children and adolescents, while focusing on the disease's etiopathogenesis, clinical manifestations, renal tissue alterations, and treatment options.