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10.1093/cid/ciy630 http://scihub22266oqcxt.onion/10.1093/cid/ciy630 30304533!ä!30304533 Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=30304533&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Clin+Infect+Dis 2019 ; 68 (5): 810-817 Nephropedia Template TP {{tp|p=30304533|t=2019. An Outbreak of Human Parvovirus B19 Hidden by Dengue Fever |pdf=|usr=}}{{30304533}} gab.com Text An Outbreak of Human Parvovirus B19 Hidden by Dengue Fever JO: Clin Infect Dis http://www.kidney.de/pget.php?&tw=1&pmid=30304533 #FOAvip BACKGROUND: Seasonal outbreaks of dengue often result in hundreds of dengue-suspected cases where a clinical diagnosis cannot be confirmed. Usually, during large outbreaks of dengue and other pathogens that can cause acute febrile illnesses, the search for secondary pathogens with similar disease outcomes is rare. METHODS: Using total RNA sequencing and targeted diagnostic assays, we discovered an outbreak of parvovirus B19 in dengue-suspected patients that occurred from November 2013 to February 2014. RESULTS: Of the 182 cases investigated, 63% were viremic for the B19 virus. Moreover, we found that >43% of infected patients had no serological evidence of prior infection. Parvovirus B19 is a typical childhood infection, yet we observed that 82% of the infected patients were adults. Additionally, we perceived that infected adults had significantly higher presentations of myalgia than in children. We also obtained viral protein (VP) 1/VP2 gene nucleotide sequences from 43 patients. CONCLUSIONS: Our results support the utility of next-generation sequencing for symptomatic patients with unknown etiologies during seasonal outbreaks of dengue and other arborviruses. Our findings could improve the vigilance of hospitals and laboratories by raising awareness of co-circulating pathogens such as parvovirus B19 that may be hidden in plain sight. Twit Text FOAVip An Outbreak of Human Parvovirus B19 Hidden by Dengue Fever ????Clin Infect Dis http://www.kidney.de/pget.php?&tw=1&pmid=30304533 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=30304533 #FOAvip English Wikipedia <ref>{{Cite pmid|30304533}}</ref> An Outbreak of Human Parvovirus B19 Hidden by Dengue Fever #MMPMID30304533 Di Paola N; Mesquita FS; Oliveira DBL; Villabona-Arenas CJ; Zaki Pour S; de Sousa-Capra C; Lopes GP; Santana RAF; Pinho JRR; Balarini K; Pereira da Fonseca CRT; Zanotto PMA Clin Infect Dis 2019[Feb]; 68 (5): 810-817 PMID30304533show ga BACKGROUND: Seasonal outbreaks of dengue often result in hundreds of dengue-suspected cases where a clinical diagnosis cannot be confirmed. Usually, during large outbreaks of dengue and other pathogens that can cause acute febrile illnesses, the search for secondary pathogens with similar disease outcomes is rare. METHODS: Using total RNA sequencing and targeted diagnostic assays, we discovered an outbreak of parvovirus B19 in dengue-suspected patients that occurred from November 2013 to February 2014. RESULTS: Of the 182 cases investigated, 63% were viremic for the B19 virus. Moreover, we found that >43% of infected patients had no serological evidence of prior infection. Parvovirus B19 is a typical childhood infection, yet we observed that 82% of the infected patients were adults. Additionally, we perceived that infected adults had significantly higher presentations of myalgia than in children. We also obtained viral protein (VP) 1/VP2 gene nucleotide sequences from 43 patients. CONCLUSIONS: Our results support the utility of next-generation sequencing for symptomatic patients with unknown etiologies during seasonal outbreaks of dengue and other arborviruses. Our findings could improve the vigilance of hospitals and laboratories by raising awareness of co-circulating pathogens such as parvovirus B19 that may be hidden in plain sight. |*Disease Outbreaks[MESH] |*Parvovirus B19, Human[MESH] |Adolescent[MESH] |Adult[MESH] |Brazil/epidemiology[MESH] |Child[MESH] |Coinfection/*epidemiology[MESH] |Dengue/*epidemiology[MESH] |Female[MESH] |Humans[MESH] |Male[MESH] |Parvoviridae Infections/*virology[MESH] |Serologic Tests[MESH]An Outbreak of Human Parvovirus B19 Hidden by Dengue Fever (epmc).pdf DeepDyve Pubget Overpricing