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10.1111/sji.12717 http://scihub22266oqcxt.onion/10.1111/sji.12717 30247785!6286684!30247785     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Scand+J+Immunol 2018 ; 88 (5): e12717 Nephropedia Template TP {{tp|p=30247785|t=2018. IFN-lambda4 inhibits HIV infection of macrophages through signalling of IFN-lambdaR1/IL-10R2 receptor complex |pdf=|usr=}}{{30247785}} gab.com Text IFN-lambda4 inhibits HIV infection of macrophages through signalling of IFN-lambdaR1/IL-10R2 receptor complex JO: Scand J Immunol http://www.kidney.de/pget.php?&tw=1&pmid=30247785 #FOAvip The recently discovered IFN-lambda4 has been found to have antiviral activity against several viruses. However, it's unknown whether IFN-lambda4 can inhibit HIV infection. Here, we show that IFN-lambda4 could suppress HIV infection of macrophages. This IFN-lambda4-mediated HIV inhibition was compromised by the antibodies against IFN-lambda receptor complex, IFN-lambdaR1/IL-10R2. IFN-lambda4 enhanced the phosphorylation of STAT1, and induced antiviral interferon-stimulated genes. These findings indicated that IFN-lambda4 can inhibit HIV via JAK/STAT signalling pathway. Twit Text FOAVip IFN-lambda4 inhibits HIV infection of macrophages through signalling of IFN-lambdaR1/IL-10R2 receptor complex ????Scand J Immunol http://www.kidney.de/pget.php?&tw=1&pmid=30247785 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=30247785 #FOAvip English Wikipedia <ref>{{Cite pmid|30247785}}</ref> IFN-lambda4 inhibits HIV infection of macrophages through signalling of IFN-lambdaR1/IL-10R2 receptor complex #MMPMID30247785 Su QJ; Wang X; Zhou RH; Guo L; Liu H; Li JL; Ho WZ Scand J Immunol 2018[Nov]; 88 (5): e12717 PMID30247785show ga The recently discovered IFN-lambda4 has been found to have antiviral activity against several viruses. However, it's unknown whether IFN-lambda4 can inhibit HIV infection. Here, we show that IFN-lambda4 could suppress HIV infection of macrophages. This IFN-lambda4-mediated HIV inhibition was compromised by the antibodies against IFN-lambda receptor complex, IFN-lambdaR1/IL-10R2. IFN-lambda4 enhanced the phosphorylation of STAT1, and induced antiviral interferon-stimulated genes. These findings indicated that IFN-lambda4 can inhibit HIV via JAK/STAT signalling pathway. |Anti-HIV Agents/*pharmacology[MESH] |HIV Infections/*immunology/metabolism/virology[MESH] |Humans[MESH] |In Vitro Techniques[MESH] |Interleukin-10 Receptor beta Subunit/*metabolism[MESH] |Interleukins/*metabolism/*pharmacology[MESH] |Macrophages/*immunology/metabolism/*virology[MESH] |Receptors, Cytokine/*metabolism[MESH] |Receptors, Interferon[MESH] |Recombinant Proteins/pharmacology[MESH] |STAT1 Transcription Factor/metabolism[MESH] |Signal Transduction[MESH]IFN-lambda4 inhibits HIV infection of macrophages through signalling o(epmc).pdf DeepDyve Pubget Overpricing