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10.1186/s41232-018-0076-7 http://scihub22266oqcxt.onion/10.1186/s41232-018-0076-7 30237829!6139938!30237829     free     free     free       Inflamm+Regen 2018 ; 38 (?): 19 Nephropedia Template TP {{tp|p=30237829|t=2018. Myeloid-derived suppressor cells in non-neoplastic inflamed organs |pdf=|usr=}}{{30237829}} gab.com Text Myeloid-derived suppressor cells in non-neoplastic inflamed organs JO: Inflamm Regen http://www.kidney.de/pget.php?&tw=1&pmid=30237829 #FOAvip BACKGROUND: Myeloid-derived suppressor cells (MDSCs) are a highly heterogeneous population of immature myeloid cells with immunosuppressive function. Although their function in tumor-bearing conditions is well studied, less is known about the role of MDSCs in various organs under non-neoplastic inflammatory conditions. MAIN BODY: MDSCs are divided into two subpopulations, G-MDSCs and M-MDSCs, and their distribution varies between organs. MDSCs negatively control inflammation in inflamed organs such as the lungs, joints, liver, kidneys, intestines, central nervous system (CNS), and eyes by suppressing T cells and myeloid cells. MDSCs also regulate fibrosis in the lungs, liver, and kidneys and help repair CNS injuries. MDSCs in organs are plastic and can differentiate into osteoclasts and tolerogenic dendritic cells according to the microenvironment under non-neoplastic inflammatory conditions. CONCLUSION: This article summarizes recent findings about MDSCs under inflammatory conditions, especially with respect to their function and differentiation in specific organs. Twit Text FOAVip Myeloid-derived suppressor cells in non-neoplastic inflamed organs ????Inflamm Regen http://www.kidney.de/pget.php?&tw=1&pmid=30237829 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=30237829 #FOAvip English Wikipedia <ref>{{Cite pmid|30237829}}</ref> Myeloid-derived suppressor cells in non-neoplastic inflamed organs #MMPMID30237829 Sendo S; Saegusa J; Morinobu A Inflamm Regen 2018[]; 38 (?): 19 PMID30237829show ga BACKGROUND: Myeloid-derived suppressor cells (MDSCs) are a highly heterogeneous population of immature myeloid cells with immunosuppressive function. Although their function in tumor-bearing conditions is well studied, less is known about the role of MDSCs in various organs under non-neoplastic inflammatory conditions. MAIN BODY: MDSCs are divided into two subpopulations, G-MDSCs and M-MDSCs, and their distribution varies between organs. MDSCs negatively control inflammation in inflamed organs such as the lungs, joints, liver, kidneys, intestines, central nervous system (CNS), and eyes by suppressing T cells and myeloid cells. MDSCs also regulate fibrosis in the lungs, liver, and kidneys and help repair CNS injuries. MDSCs in organs are plastic and can differentiate into osteoclasts and tolerogenic dendritic cells according to the microenvironment under non-neoplastic inflammatory conditions. CONCLUSION: This article summarizes recent findings about MDSCs under inflammatory conditions, especially with respect to their function and differentiation in specific organs. ?Myeloid-derived suppressor cells in non-neoplastic inflamed organs (epmc).pdf DeepDyve Pubget Overpricing