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10.1007/s00401-018-1909-9 http://scihub22266oqcxt.onion/10.1007/s00401-018-1909-9 30219940/?report=reader!6208726!30219940     free     free     free       Acta+Neuropathol 2018 ; 136 (5): 691-697 Nephropedia Template TP {{tp|p=30219940|t=2018. Nodding syndrome in Uganda is a tauopathy |pdf=|usr=}}{{30219940}} gab.com Text Nodding syndrome in Uganda is a tauopathy JO: Acta Neuropathol http://www.kidney.de/pget.php?&tw=1&pmid=30219940 #FOAvip Nodding syndrome is an epidemic neurologic disorder of unknown cause that affects children in the subsistence-farming communities of East Africa. We report the neuropathologic findings in five fatal cases (13-18 years of age at death) of nodding syndrome from the Acholi people in northern Uganda. Neuropathologic examination revealed tau-immunoreactive neuronal neurofibrillary tangles, pre-tangles, neuropil threads, and dot-like lesions involving the cerebral cortex, subcortical nuclei and brainstem. There was preferential involvement of the frontal and temporal lobes in a patchy distribution, mostly involving the crests of gyri and the superficial cortical lamina. The mesencephalopontine tegmental nuclei, substantia nigra, and locus coeruleus revealed globose neurofibrillary tangles and threads. We conclude that nodding syndrome is a tauopathy and may represent a newly recognized neurodegenerative disease. Twit Text FOAVip Nodding syndrome in Uganda is a tauopathy ????Acta Neuropathol http://www.kidney.de/pget.php?&tw=1&pmid=30219940 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=30219940 #FOAvip English Wikipedia <ref>{{Cite pmid|30219940}}</ref> Nodding syndrome in Uganda is a tauopathy #MMPMID30219940 Pollanen MS; Onzivua S; Robertson J; McKeever PM; Olawa F; Kitara DL; Fong A Acta Neuropathol 2018[Nov]; 136 (5): 691-697 PMID30219940show ga Nodding syndrome is an epidemic neurologic disorder of unknown cause that affects children in the subsistence-farming communities of East Africa. We report the neuropathologic findings in five fatal cases (13-18 years of age at death) of nodding syndrome from the Acholi people in northern Uganda. Neuropathologic examination revealed tau-immunoreactive neuronal neurofibrillary tangles, pre-tangles, neuropil threads, and dot-like lesions involving the cerebral cortex, subcortical nuclei and brainstem. There was preferential involvement of the frontal and temporal lobes in a patchy distribution, mostly involving the crests of gyri and the superficial cortical lamina. The mesencephalopontine tegmental nuclei, substantia nigra, and locus coeruleus revealed globose neurofibrillary tangles and threads. We conclude that nodding syndrome is a tauopathy and may represent a newly recognized neurodegenerative disease. |Adolescent[MESH] |Brain/metabolism/*pathology[MESH] |Female[MESH] |Humans[MESH] |Male[MESH] |Neurofibrillary Tangles/*pathology[MESH] |Nodding Syndrome/epidemiology/*pathology/*physiopathology[MESH] |Tauopathies/epidemiology/*physiopathology[MESH]Nodding syndrome in Uganda is a tauopathy (epmc).pdf DeepDyve Pubget Overpricing