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10.3892/etm.2018.6476

http://scihub22266oqcxt.onion/10.3892/etm.2018.6476
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30186495!6122502!30186495
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suck abstract from ncbi

pmid30186495      Exp+Ther+Med 2018 ; 16 (3): 2639-2644
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  • Complement 3 glomerulonephritis in rheumatoid arthritis: A case report and follow-up #MMPMID30186495
  • Wang X; Han L; Li H; Zhang D
  • Exp Ther Med 2018[Sep]; 16 (3): 2639-2644 PMID30186495show ga
  • Glomerulonephritis (GN) caused by rheumatoid arthritis may manifest as various pathological types; however, to the best of our knowledge, rheumatoid arthritis-associated complement 3 (C3)-GN has not been reported by any previous studies. C3GN is caused by dysregulation of the alternative pathway of complements, which is completely different from activation of the classic pathway of a typical autoimmune disease to cause renal damage. The present study describes a patient with a history of rheumatoid arthritis for 18 years, who presented with edema, proteinuria, hematuria, hypoproteinemia and a hypocomplementemic state. The pathological diagnosis was C3GN based on histological examination of a renal biopsy specimen. Hormone treatment on its own appeared to be effective and achieved complete clinical remission, while the follow-up of the condition remained stable.
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