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10.1111/tbed.13008

http://scihub22266oqcxt.onion/10.1111/tbed.13008
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30171801!7168530!30171801
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suck abstract from ncbi


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pmid30171801      Transbound+Emerg+Dis 2019 ; 66 (2): 687-695
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  • Retrospective detection and phylogenetic analysis of swine acute diarrhoea syndrome coronavirus in pigs in southern China #MMPMID30171801
  • Zhou L; Sun Y; Lan T; Wu R; Chen J; Wu Z; Xie Q; Zhang X; Ma J
  • Transbound Emerg Dis 2019[Mar]; 66 (2): 687-695 PMID30171801show ga
  • Swine acute diarrhoea syndrome coronavirus (SADS-CoV), a novel coronavirus, was first discovered in southern China in January 2017 and caused a large scale outbreak of fatal diarrheal disease in piglets. Here, we conducted a retrospective investigation of 236 samples from 45 swine farms with a clinical history of diarrheal disease to evaluate the emergence and the distribution of SADS-CoV in pigs in China. Our results suggest that SADS-CoV has emerged in China at least since August 2016. Meanwhile, we detected a prevalence of SADS-CoV (43.53%), porcine deltacoronavirus (8.83%), porcine epidemic diarrhoea virus (PEDV) (78.25%), rotavirus (21.77%), and transmissible gastroenteritis virus (0%), and we also found the co-infection of SADS-CoV and PEDV occurred most frequently with the rate of 17.65%. We screened and obtained two new complete genomes, five N and five S genes of SADS-CoV. Phylogenetic analysis based on these sequences revealed that all SADS-CoV sequences in this study clustered with previously reported SADS-CoV strains to form a well defined branch that grouped with the bat coronavirus HKU2 strains. This study is the first retrospective investigation for SADS-CoV and provides the epidemiological information of this new virus in China, which highlights the urgency to develop effective measures to control SADS-CoV.
  • |*Genome, Viral[MESH]
  • |Alphacoronavirus/classification/*genetics/*isolation & purification[MESH]
  • |Animals[MESH]
  • |China/epidemiology[MESH]
  • |Coronavirus Infections/epidemiology/*veterinary/virology[MESH]
  • |Coronavirus Nucleocapsid Proteins[MESH]
  • |Feces/virology[MESH]
  • |Female[MESH]
  • |Nucleocapsid Proteins/analysis[MESH]
  • |Phylogeny[MESH]
  • |Polymerase Chain Reaction/veterinary[MESH]
  • |Prevalence[MESH]
  • |Retrospective Studies[MESH]
  • |Spike Glycoprotein, Coronavirus/analysis[MESH]
  • |Swine[MESH]


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