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10.1002/pbc.27344 http://scihub22266oqcxt.onion/10.1002/pbc.27344 30070073!7168068!30070073     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Pediatr+Blood+Cancer 2018 ; 65 (11): e27344 Nephropedia Template TP {{tp|p=30070073|t=2018. Is an infectious trigger always required for primary hemophagocytic lymphohistiocytosis? Lessons from in utero and neonatal disease |pdf=|usr=}}{{30070073}} gab.com Text Is an infectious trigger always required for primary hemophagocytic lymphohistiocytosis Lessons from in utero and neonatal disease JO: Pediatr Blood Cancer http://www.kidney.de/pget.php?&tw=1&pmid=30070073 #FOAvip In this report, we evaluate the hypothesis that hemophagocytic lymphohistiocytosis in patients with defects of lymphocyte cytotoxicity is usually triggered by infections. We show that in the majority of patients, extensive virus PCR panels performed in addition to routine microbiological investigations remain negative and summarize 25 patients with onset of hemophagocytic lymphohistiocytosis in utero or within the first 10 days of life, in none of which an associated bacterial or viral infection was reported. These observations, even though preliminary, invite to consider a key role of lymphocyte cytotoxicity in controlling T-cell homeostasis also in the absence of apparent infectious stimuli. Twit Text FOAVip Is an infectious trigger always required for primary hemophagocytic lymphohistiocytosis Lessons from in utero and neonatal disease ????Pediatr Blood Cancer http://www.kidney.de/pget.php?&tw=1&pmid=30070073 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=30070073 #FOAvip English Wikipedia <ref>{{Cite pmid|30070073}}</ref> Is an infectious trigger always required for primary hemophagocytic lymphohistiocytosis? Lessons from in utero and neonatal disease #MMPMID30070073 Heeg M; Ammann S; Klemann C; Panning M; Falcone V; Hengel H; Lehmberg K; Zur Stadt U; Wustrau K; Janka G; Ehl S Pediatr Blood Cancer 2018[Nov]; 65 (11): e27344 PMID30070073show ga In this report, we evaluate the hypothesis that hemophagocytic lymphohistiocytosis in patients with defects of lymphocyte cytotoxicity is usually triggered by infections. We show that in the majority of patients, extensive virus PCR panels performed in addition to routine microbiological investigations remain negative and summarize 25 patients with onset of hemophagocytic lymphohistiocytosis in utero or within the first 10 days of life, in none of which an associated bacterial or viral infection was reported. These observations, even though preliminary, invite to consider a key role of lymphocyte cytotoxicity in controlling T-cell homeostasis also in the absence of apparent infectious stimuli. |Bacterial Infections/epidemiology[MESH] |Child[MESH] |Female[MESH] |Fetus[MESH] |Humans[MESH] |Infant[MESH] |Infant, Newborn[MESH] |Infant, Newborn, Diseases/etiology[MESH] |Lymphohistiocytosis, Hemophagocytic/*etiology[MESH] |Male[MESH] |Pregnancy[MESH] |Virus Diseases/epidemiology[MESH]Is an infectious trigger always required for primary hemophagocytic l(epmc).pdf DeepDyve Pubget Overpricing