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10.1093/cid/ciy596

http://scihub22266oqcxt.onion/10.1093/cid/ciy596
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30052873!ä!30052873

suck abstract from ncbi


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pmid30052873      Clin+Infect+Dis 2019 ; 68 (6): 1001-1008
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  • Infection Pressure in Men Who Have Sex With Men and Their Suitability to Donate Blood #MMPMID30052873
  • van Bilsen WPH; Zaaijer HL; Matser A; van den Hurk K; Slot E; Schim van der Loeff MF; Prins M; van de Laar TJW
  • Clin Infect Dis 2019[Mar]; 68 (6): 1001-1008 PMID30052873show ga
  • BACKGROUND: Deferral of men who have sex with men (MSM) from blood donation is highly debated. We therefore investigated their suitability to donate blood. METHODS: We compared the antibody prevalence of 10 sexually and transfusion-transmissible infections (TTIs) among 583 MSM and 583 age-matched repeat male blood donors. MSM were classified as low risk (lr) or medium-to-high risk (hr) based on self-reported sexual behavior and as qualified or unqualified using Dutch donor deferral criteria. Infection pressure (IP) was defined as the number of antibody-reactive infections, with class A infections (human immunodeficiency virus-1/2, hepatitis B virus, hepatitis C virus, human T-cell lymphotropic virus-1/2, syphilis) given double weight compared to class B infections (cytomegalovirus, herpes simplex virus-1/2, human herpesvirus 8, hepatitis E virus, parvovirus B19). RESULTS: Donors had a lower median IP than qualified lr-MSM and qualified hr-MSM (2 [interquartile range IQR, 1-2] vs 3 [IQR, 2-4]; P < .001). Low IP was found in 76% of donors, 39% of qualified lr-MSM, and 27% of qualified hr-MSM. The prevalence of class A infections did not differ between donors and qualified lr-MSM but was significantly higher in qualified hr-MSM and unqualified MSM. Recently acquired class A infections were detected in hr-MSM only. Compared to blood donors, human herpesviruses were more prevalent in all MSM groups (P < .001). CONCLUSIONS: IP correlates with self-reported risk behavior among MSM. Although lr-MSM might form a low threat for blood safety with regard to class A infections, the high seroprevalence of human herpesviruses in lr-MSM warrants further investigation.
  • |*Blood Donors/psychology[MESH]
  • |*Homosexuality, Male/psychology[MESH]
  • |*Peer Influence[MESH]
  • |Adult[MESH]
  • |Coinfection[MESH]
  • |Communicable Diseases/*epidemiology/*psychology/transmission[MESH]
  • |Humans[MESH]
  • |Incidence[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Registries[MESH]
  • |Risk Assessment[MESH]
  • |Risk Factors[MESH]
  • |Risk-Taking[MESH]


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