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10.1016/0165-2478(85)90171-3 http://scihub22266oqcxt.onion/10.1016/0165-2478(85)90171-3 3002974!7119846!3002974     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Immunol+Lett 1985 ; 11 (3-4): 219-24 Nephropedia Template TP {{tp|p=3002974|t=1985. Genetic aspects of macrophage involvement in natural resistance to virus infections |pdf=|usr=}}{{3002974}} gab.com Text Genetic aspects of macrophage involvement in natural resistance to virus infections JO: Immunol Lett http://www.kidney.de/pget.php?&tw=1&pmid=3002974 #FOAvip Macrophages are thought to constitute an important element in the body's natural defense against invasion and dissemination of viruses. Possible antiviral mechanisms of macrophages are defined and referred to as intrinsic, i.e. the ability of macrophages to serve as a nonpermissive barrier between the virus and susceptible cells and extrinsic, i.e. the ability of macrophages to affect the virus or virus replication in surrounding cells. Most studies on the role of macrophages in natural resistance to virus infections have been performed in animal models. An interesting aspect of many viral infections in animals is the finding of a genetically determined variation in natural resistance. Because of the availability of numerous inbred and congenic strains most studies on genetically determined resistance have been performed in mice. The classical examples are resistance to flaviviruses and susceptibility to mouse hepatitis virus, both of which are inherited as dominant, monogenic traits. With these viruses macrophage intrinsic restriction of virus replication has been found to express at the cellular level the genetics of resistance/susceptibility seen in the intact animal. Other examples, where macrophages have been implicated in genetically determined resistance include herpes simplex virus and influenza virus. The involvement of macrophages in natural resistance to these viruses is discussed in relation to other putative resistance determinants like interferon production and sensitivity and natural killer cell activity. Twit Text FOAVip Genetic aspects of macrophage involvement in natural resistance to virus infections ????Immunol Lett http://www.kidney.de/pget.php?&tw=1&pmid=3002974 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=3002974 #FOAvip English Wikipedia <ref>{{Cite pmid|3002974}}</ref> Genetic aspects of macrophage involvement in natural resistance to virus infections #MMPMID3002974 Mogensen SC Immunol Lett 1985[]; 11 (3-4): 219-24 PMID3002974show ga Macrophages are thought to constitute an important element in the body's natural defense against invasion and dissemination of viruses. Possible antiviral mechanisms of macrophages are defined and referred to as intrinsic, i.e. the ability of macrophages to serve as a nonpermissive barrier between the virus and susceptible cells and extrinsic, i.e. the ability of macrophages to affect the virus or virus replication in surrounding cells. Most studies on the role of macrophages in natural resistance to virus infections have been performed in animal models. An interesting aspect of many viral infections in animals is the finding of a genetically determined variation in natural resistance. Because of the availability of numerous inbred and congenic strains most studies on genetically determined resistance have been performed in mice. The classical examples are resistance to flaviviruses and susceptibility to mouse hepatitis virus, both of which are inherited as dominant, monogenic traits. With these viruses macrophage intrinsic restriction of virus replication has been found to express at the cellular level the genetics of resistance/susceptibility seen in the intact animal. Other examples, where macrophages have been implicated in genetically determined resistance include herpes simplex virus and influenza virus. The involvement of macrophages in natural resistance to these viruses is discussed in relation to other putative resistance determinants like interferon production and sensitivity and natural killer cell activity. |Animals[MESH] |Coronaviridae Infections/genetics/immunology[MESH] |Flavivirus[MESH] |Herpesviridae Infections/genetics/immunology[MESH] |Immunity, Innate[MESH] |Macrophages/*immunology/microbiology[MESH] |Mice[MESH] |Orthomyxoviridae Infections/genetics/immunology[MESH] |Togaviridae Infections/genetics/immunology[MESH] |Virus Diseases/genetics/*immunology/microbiology[MESH]Genetic aspects of macrophage involvement in natural resistance to vir(epmc).pdf DeepDyve Pubget Overpricing