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10.1016/j.dadm.2018.03.005

http://scihub22266oqcxt.onion/10.1016/j.dadm.2018.03.005
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suck abstract from ncbi


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pmid30014034      Alzheimers+Dement+(Amst) 2018 ; 10 (ä): 358-362
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  • Understanding hallucinations in probable Alzheimer s disease: Very low prevalence rates in a tertiary memory clinic #MMPMID30014034
  • Linszen MMJ; Lemstra AW; Dauwan M; Brouwer RM; Scheltens P; Sommer IEC
  • Alzheimers Dement (Amst) 2018[]; 10 (ä): 358-362 PMID30014034show ga
  • INTRODUCTION: Averaging at 13.4%, current literature reports widely varying prevalence rates of hallucinations in patients with probable Alzheimer's disease (AD), and is still inconclusive on contributive factors to hallucinations in AD. METHODS: This study assessed prevalence, associated factors and clinical characteristics of hallucinations in 1227 patients with probable AD, derived from a tertiary memory clinic specialized in early diagnosis of dementia. Hallucinations were assessed with the Neuropsychiatric Inventory. RESULTS: Hallucination prevalence was very low, with only 4.5% (n = 55/1227) affected patients. Hallucinations were mostly visual (n = 40/55) or auditory (n = 12/55). Comorbid delusions were present in over one-third of cases (n = 23/55).Hallucinations were associated with increased dementia severity, neuropsychiatric symptoms, and a lifetime history of hallucination-evoking disease (such as depression and sensory impairment), but not with age or gender. DISCUSSION: In the largest sample thus far, we report a low prevalence of hallucinations in probable AD patients, comparable to rates in non-demented elderly. Our results suggest that hallucinations are uncommon in early stage AD. Clinicians that encounter hallucinations in patients with early AD should be sensitive to hallucination-evoking comorbidity.
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