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10.4314/ahs.v17i4.17 http://scihub22266oqcxt.onion/10.4314/ahs.v17i4.17 29937880!5870291!29937880     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=29937880&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       Afr+Health+Sci 2017 ; 17 (4): 1092-1100 Nephropedia Template TP {{tp|p=29937880|t=2017. QTc prolongation in Black diabetic subjects with cardiac autonomic neuropathy |pdf=|usr=}}{{29937880}} gab.com Text QTc prolongation in Black diabetic subjects with cardiac autonomic neuropathy JO: Afr Health Sci http://www.kidney.de/pget.php?&tw=1&pmid=29937880 #FOAvip BACKGROUND: Prolonged corrected QT (QTc) has been identified as a risk factor for malignant arrhythmias and sudden cardiac death. Caucasian studies have shown a definite relationship between QTc prolongation and Cardiac Autonomic Neuropathy (CAN) in diabetic subjects. OBJECTIVE: To determine the prevalence of prolonged QTc in Black diabetic individuals with CAN and to ascertain how prolonged QTc correlated with the severity of CAN among these patients. METHODS: A total of 176 adult diabetic subjects were studied, 87 males and 89 females. There was a control group of non-diabetic individuals. Cardiac autonomic function was assessed using five cardiovascular autonomic function tests. CAN was diagnosed if 2 or more of these tests were abnormal. Severity of CAN was determined according to the number of abnormal tests. QTc > 0.440 was regarded as prolonged. RESULTS: Fifty-one out of the 176 diabetic subjects (29%) had CAN. The prevalence of prolonged QTc in diabetic subjects with CAN was 12%. QTc was prolonged in 1.6% and 0.6% of diabetic individuals without CAN and controls respectively. Although QTc correlated strongly with cardiac autonomic function neuropathy, there was no definite relationship between QTc prolongation and severity of CAN. CONCLUSION: This study in a Black population is in agreement with the well-known relationship between QTc prolongation and CAN reported in Caucasian studies. In view of the wide variability of QTc in this study population, it is suggested that relative QTc increase may be a better indicator of CAN than a definite QTc prolongation of greater than 0.440. Twit Text FOAVip QTc prolongation in Black diabetic subjects with cardiac autonomic neuropathy ????Afr Health Sci http://www.kidney.de/pget.php?&tw=1&pmid=29937880 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29937880 #FOAvip English Wikipedia <ref>{{Cite pmid|29937880}}</ref> QTc prolongation in Black diabetic subjects with cardiac autonomic neuropathy #MMPMID29937880 Ukpabi OJ; Onwubere BJ Afr Health Sci 2017[Dec]; 17 (4): 1092-1100 PMID29937880show ga BACKGROUND: Prolonged corrected QT (QTc) has been identified as a risk factor for malignant arrhythmias and sudden cardiac death. Caucasian studies have shown a definite relationship between QTc prolongation and Cardiac Autonomic Neuropathy (CAN) in diabetic subjects. OBJECTIVE: To determine the prevalence of prolonged QTc in Black diabetic individuals with CAN and to ascertain how prolonged QTc correlated with the severity of CAN among these patients. METHODS: A total of 176 adult diabetic subjects were studied, 87 males and 89 females. There was a control group of non-diabetic individuals. Cardiac autonomic function was assessed using five cardiovascular autonomic function tests. CAN was diagnosed if 2 or more of these tests were abnormal. Severity of CAN was determined according to the number of abnormal tests. QTc > 0.440 was regarded as prolonged. RESULTS: Fifty-one out of the 176 diabetic subjects (29%) had CAN. The prevalence of prolonged QTc in diabetic subjects with CAN was 12%. QTc was prolonged in 1.6% and 0.6% of diabetic individuals without CAN and controls respectively. Although QTc correlated strongly with cardiac autonomic function neuropathy, there was no definite relationship between QTc prolongation and severity of CAN. CONCLUSION: This study in a Black population is in agreement with the well-known relationship between QTc prolongation and CAN reported in Caucasian studies. In view of the wide variability of QTc in this study population, it is suggested that relative QTc increase may be a better indicator of CAN than a definite QTc prolongation of greater than 0.440. |Adult[MESH] |Autonomic Nervous System Diseases/*diagnosis[MESH] |Black People[MESH] |Blood Pressure[MESH] |Diabetes Complications/diagnosis/*ethnology[MESH] |Diabetic Cardiomyopathies/diagnosis/*ethnology[MESH] |Diabetic Neuropathies/*physiopathology[MESH] |Electrocardiography[MESH] |Female[MESH] |Heart Rate/*physiology[MESH] |Heart/*physiopathology[MESH] |Humans[MESH] |Long QT Syndrome/blood/*physiopathology[MESH] |Male[MESH]QTc prolongation in Black diabetic subjects with cardiac autonomic neu(epmc).pdf DeepDyve Pubget Overpricing