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10.1016/j.det.2018.02.007

http://scihub22266oqcxt.onion/10.1016/j.det.2018.02.007
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29929599!ä!29929599

suck abstract from ncbi


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pmid29929599      Dermatol+Clin 2018 ; 36 (3): 277-292
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  • End-Stage Renal Disease Chronic Itch and Its Management #MMPMID29929599
  • Reszke R; Szepietowski JC
  • Dermatol Clin 2018[Jul]; 36 (3): 277-292 PMID29929599show ga
  • End-stage renal disease chronic itch is a frequent symptom that bothers patients with advanced stages of chronic kidney disease. The pathogenesis of the chronic itch symptom is complex and not yet fully understood and includes many metabolic, immunologic, and neurogenic factors. A significant burden of the disease results in decreased quality of life with sleep impairment, depressive symptoms, and increased mortality of affected individuals. No treatment of choice is available; topical therapy (emollients), phototherapy (UV-B), and systemic therapy (antiepileptics, opioid agonists, and antagonists) provide significant relief in varying percentages of patients.
  • |*Ultraviolet Therapy[MESH]
  • |Amines/therapeutic use[MESH]
  • |Analgesics, Opioid/therapeutic use[MESH]
  • |Anticonvulsants/therapeutic use[MESH]
  • |Antipruritics/*therapeutic use[MESH]
  • |Chronic Disease[MESH]
  • |Cyclohexanecarboxylic Acids/therapeutic use[MESH]
  • |Emollients/therapeutic use[MESH]
  • |Gabapentin[MESH]
  • |Humans[MESH]
  • |Kidney Failure, Chronic/*complications/physiopathology/therapy[MESH]
  • |Nalbuphine/therapeutic use[MESH]
  • |Narcotic Antagonists/therapeutic use[MESH]
  • |Pregabalin/therapeutic use[MESH]
  • |Pruritus/*etiology/physiopathology/*therapy[MESH]
  • |Quality of Life[MESH]
  • |Renal Dialysis[MESH]
  • |Severity of Illness Index[MESH]


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