Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1039/c7sc03954a http://scihub22266oqcxt.onion/10.1039/c7sc03954a 29619172!5858021!29619172     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 251.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Chem+Sci 2017 ; 8 (12): 8255-8264 Nephropedia Template TP {{tp|p=29619172|t=2017. Visualization of long-term Mg(2+) dynamics in apoptotic cells using a novel targetable fluorescent probe |pdf=|usr=}}{{29619172}} gab.com Text Visualization of long-term Mg(2+) dynamics in apoptotic cells using a novel targetable fluorescent probe JO: Chem Sci http://www.kidney.de/pget.php?&tw=1&pmid=29619172 #FOAvip Mg(2+) plays important roles in many physiological processes. However, the underlying molecular mechanisms, especially in the apoptotic pathway, remain unclear due to the diffusion of Mg(2+) probes, which hinders long-term imaging in specific organelles. We developed an immobilized Mg(2+) probe, MGH, which is covalently conjugated with the HaloTag protein in various organelles. HaloTag-coupled MGH enabled long-term imaging of intracellular local Mg(2+) dynamics for 24 h. To exploit this remarkable property, MGH was applied to the investigation of intracellular Mg(2+) dynamics during apoptosis. Time-lapse imaging revealed an increase in the Mg(2+) concentration after apoptotic cell shrinkage. Combined imaging analyses of intracellular Mg(2+) and ATP concentrations strongly suggested that this Mg(2+) concentration increase was caused by the dissociation of Mg(2+) from ATP, along with a decrease in the intracellular ATP concentration. Thus, this protein-coupled Mg(2+) probe could be a new chemical tool to elucidate intracellular Mg(2+) dynamics with high spatiotemporal resolution. Twit Text FOAVip Visualization of long-term Mg(2+) dynamics in apoptotic cells using a novel targetable fluorescent probe ????Chem Sci http://www.kidney.de/pget.php?&tw=1&pmid=29619172 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29619172 #FOAvip English Wikipedia <ref>{{Cite pmid|29619172}}</ref> Visualization of long-term Mg(2+) dynamics in apoptotic cells using a novel targetable fluorescent probe #MMPMID29619172 Matsui Y; Funato Y; Imamura H; Miki H; Mizukami S; Kikuchi K Chem Sci 2017[Dec]; 8 (12): 8255-8264 PMID29619172show ga Mg(2+) plays important roles in many physiological processes. However, the underlying molecular mechanisms, especially in the apoptotic pathway, remain unclear due to the diffusion of Mg(2+) probes, which hinders long-term imaging in specific organelles. We developed an immobilized Mg(2+) probe, MGH, which is covalently conjugated with the HaloTag protein in various organelles. HaloTag-coupled MGH enabled long-term imaging of intracellular local Mg(2+) dynamics for 24 h. To exploit this remarkable property, MGH was applied to the investigation of intracellular Mg(2+) dynamics during apoptosis. Time-lapse imaging revealed an increase in the Mg(2+) concentration after apoptotic cell shrinkage. Combined imaging analyses of intracellular Mg(2+) and ATP concentrations strongly suggested that this Mg(2+) concentration increase was caused by the dissociation of Mg(2+) from ATP, along with a decrease in the intracellular ATP concentration. Thus, this protein-coupled Mg(2+) probe could be a new chemical tool to elucidate intracellular Mg(2+) dynamics with high spatiotemporal resolution. äVisualization of long-term Mg(2+) dynamics in apoptotic cells using a (epmc).pdf DeepDyve Pubget Overpricing