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10.2147/IJNRD.S154000 http://scihub22266oqcxt.onion/10.2147/IJNRD.S154000 29497325!5818843!29497325     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=29497325&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Int+J+Nephrol+Renovasc+Dis 2018 ; 11 (ä): 81-92 Nephropedia Template TP {{tp|p=29497325|t=2018. The importance of the thick ascending limb of Henle s loop in renal physiology and pathophysiology |pdf=|usr=}}{{29497325}} gab.com Text The importance of the thick ascending limb of Henle s loop in renal physiology and pathophysiology JO: Int J Nephrol Renovasc Dis http://www.kidney.de/pget.php?&tw=1&pmid=29497325 #FOAvip The thick ascending limb (TAL) of Henle's loop is a crucial segment for many tasks of the nephron. Indeed, the TAL is not only a mainstay for reabsorption of sodium (Na(+)), potassium (K(+)), and divalent cations such as calcium (Ca(2+)) and magnesium (Mg(2+)) from the luminal fluid, but also has an important role in urine concentration, overall acid-base homeostasis, and ammonia cycle. Transcellular Na(+) transport along the TAL is a prerequisite for Na(+), K(+), Ca(2+), Mg(2+) homeostasis, and water reabsorption, the latter through its contribution in the generation of the cortico-medullar osmotic gradient. The role of this nephron site in acid-base balance, via bicarbonate reabsorption and acid secretion, is sometimes misunderstood by clinicians. This review describes in detail these functions, reporting in addition to the well-known molecular mechanisms, some novel findings from the current literature; moreover, the pathophysiology and the clinical relevance of primary or acquired conditions caused by TAL dysfunction are discussed. Knowing the physiology of the TAL is fundamental for clinicians, for a better understanding and management of rare and common conditions, such as tubulopathies, hypertension, and loop diuretics abuse. Twit Text FOAVip The importance of the thick ascending limb of Henle s loop in renal physiology and pathophysiology ????Int J Nephrol Renovasc Dis http://www.kidney.de/pget.php?&tw=1&pmid=29497325 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29497325 #FOAvip English Wikipedia <ref>{{Cite pmid|29497325}}</ref> The importance of the thick ascending limb of Henle s loop in renal physiology and pathophysiology #MMPMID29497325 Zacchia M; Capolongo G; Rinaldi L; Capasso G Int J Nephrol Renovasc Dis 2018[]; 11 (ä): 81-92 PMID29497325show ga The thick ascending limb (TAL) of Henle's loop is a crucial segment for many tasks of the nephron. Indeed, the TAL is not only a mainstay for reabsorption of sodium (Na(+)), potassium (K(+)), and divalent cations such as calcium (Ca(2+)) and magnesium (Mg(2+)) from the luminal fluid, but also has an important role in urine concentration, overall acid-base homeostasis, and ammonia cycle. Transcellular Na(+) transport along the TAL is a prerequisite for Na(+), K(+), Ca(2+), Mg(2+) homeostasis, and water reabsorption, the latter through its contribution in the generation of the cortico-medullar osmotic gradient. The role of this nephron site in acid-base balance, via bicarbonate reabsorption and acid secretion, is sometimes misunderstood by clinicians. This review describes in detail these functions, reporting in addition to the well-known molecular mechanisms, some novel findings from the current literature; moreover, the pathophysiology and the clinical relevance of primary or acquired conditions caused by TAL dysfunction are discussed. Knowing the physiology of the TAL is fundamental for clinicians, for a better understanding and management of rare and common conditions, such as tubulopathies, hypertension, and loop diuretics abuse. äThe importance of the thick ascending limb of Henle s loop in renal ph(epmc).pdf DeepDyve Pubget Overpricing