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10.1007/s13205-017-1079-9 http://scihub22266oqcxt.onion/10.1007/s13205-017-1079-9 29354360Humanleukocyteantigen(HLA-F)polymorphismisassociatedwithchronicHBVinfection.!5752667!29354360     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       3+Biotech 2018 ; 8 (1): 49 Nephropedia Template TP {{tp|p=29354360|t=2018. Human leukocyte antigen (HLA-F) polymorphism is associated with chronic HBV infection |pdf=|usr=}}{{29354360}} gab.com Text Human leukocyte antigen (HLA-F) polymorphism is associated with chronic HBV infection JO: 3 Biotech http://www.kidney.de/pget.php?&tw=1&pmid=29354360 #FOAvip Human leukocyte antigen (HLA)-F has been involved in immune regulation of infectious diseases. However, the role of HLA-F polymorphisms in hepatitis B infection outcomes remains unclear. Here, we aimed to determine HLA-F polymorphism implication in chronic HBV. Genotype analysis was performed for three single nucleotide polymorphisms (SNPs) of HLA-F and one SNP of HLA-E using PCR-SSP, in 252 Tunisian patients with chronic HBV infection stratified according to their HBV DNA levels (140 patients with low HBV DNA levels < 2000 IU/mL and 112 patients with high HBV DNA levels >/= 2000 IU/mL) and 240 healthy controls (CTRL). The three HLA-F SNPs (HLA-F*01:02, -F*01:03 and -F*01:04) have the same allelic and genotypic frequencies in patients and in CTRL. We reported a low HLA-F*01:02 and F*01:04 allelic frequencies in the Tunisian population; however, high HLA-F*01:03 allele frequencies were observed (17%). A significant association was found between the HLA-F*01:03 allele and decreased level of HBV DNA (P = 0.02 OR 0.56, 95% CI 0.35-0.92). No significant differences were observed in haplotype distribution between patients and CTRL. A significant association of HLA-F*01:03 with the level of HBV DNA suggests an important role of HLA-F in HBV replication control. Twit Text FOAVip Human leukocyte antigen (HLA-F) polymorphism is associated with chronic HBV infection ????3 Biotech http://www.kidney.de/pget.php?&tw=1&pmid=29354360 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29354360 #FOAvip English Wikipedia <ref>{{Cite pmid|29354360}}</ref> Human leukocyte antigen (HLA-F) polymorphism is associated with chronic HBV infection #MMPMID29354360 Laaribi AB; Hannachi N; Ben Yahia H; Marzouk M; Mehri A; Belhadj M; Yacoub S; Letaief A; Ouzari HI; Boudabous A; Boukadida J; Rizzo R; Zidi I 3 Biotech 2018[Jan]; 8 (1): 49 PMID29354360show ga Human leukocyte antigen (HLA)-F has been involved in immune regulation of infectious diseases. However, the role of HLA-F polymorphisms in hepatitis B infection outcomes remains unclear. Here, we aimed to determine HLA-F polymorphism implication in chronic HBV. Genotype analysis was performed for three single nucleotide polymorphisms (SNPs) of HLA-F and one SNP of HLA-E using PCR-SSP, in 252 Tunisian patients with chronic HBV infection stratified according to their HBV DNA levels (140 patients with low HBV DNA levels < 2000 IU/mL and 112 patients with high HBV DNA levels >/= 2000 IU/mL) and 240 healthy controls (CTRL). The three HLA-F SNPs (HLA-F*01:02, -F*01:03 and -F*01:04) have the same allelic and genotypic frequencies in patients and in CTRL. We reported a low HLA-F*01:02 and F*01:04 allelic frequencies in the Tunisian population; however, high HLA-F*01:03 allele frequencies were observed (17%). A significant association was found between the HLA-F*01:03 allele and decreased level of HBV DNA (P = 0.02 OR 0.56, 95% CI 0.35-0.92). No significant differences were observed in haplotype distribution between patients and CTRL. A significant association of HLA-F*01:03 with the level of HBV DNA suggests an important role of HLA-F in HBV replication control. äHuman leukocyte antigen (HLA-F) polymorphism is associated with chroni(epmc).pdf DeepDyve Pubget Overpricing