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10.1007/s00223-017-0372-2

http://scihub22266oqcxt.onion/10.1007/s00223-017-0372-2
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suck abstract from ncbi


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pmid29238848      Calcif+Tissue+Int 2018 ; 102 (2): 174-195
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  • Biology of Bone Sarcomas and New Therapeutic Developments #MMPMID29238848
  • Brown HK; Schiavone K; Gouin F; Heymann MF; Heymann D
  • Calcif Tissue Int 2018[Feb]; 102 (2): 174-195 PMID29238848show ga
  • Bone sarcomas are tumours belonging to the family of mesenchymal tumours and constitute a highly heterogeneous tumour group. The three main bone sarcomas are osteosarcoma, Ewing sarcoma and chondrosarcoma each subdivided in diverse histological entities. They are clinically characterised by a relatively high morbidity and mortality, especially in children and adolescents. Although these tumours are histologically, molecularly and genetically heterogeneous, they share a common involvement of the local microenvironment in their pathogenesis. This review gives a brief overview of their specificities and summarises the main therapeutic advances in the field of bone sarcoma.
  • |Bone Neoplasms/diagnosis/drug therapy/*etiology/therapy[MESH]
  • |Female[MESH]
  • |Giant Cell Tumor of Bone/pathology[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Sarcoma/diagnosis/drug therapy/*etiology/therapy[MESH]


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