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10.1016/j.conb.2017.09.010 http://scihub22266oqcxt.onion/10.1016/j.conb.2017.09.010 29024871!5732842!29024871     free     free     free       Curr+Opin+Neurobiol 2017 ; 47 (ä): 65-72 Nephropedia Template TP {{tp|p=29024871|t=2017. Brain energetics during the sleep-wake cycle |pdf=|usr=}}{{29024871}} gab.com Text Brain energetics during the sleep-wake cycle JO: Curr Opin Neurobiol http://www.kidney.de/pget.php?&tw=1&pmid=29024871 #FOAvip Brain activity during wakefulness is associated with high metabolic rates that are believed to support information processing and memory encoding. In spite of loss of consciousness, sleep still carries a substantial energy cost. Experimental evidence supports a cerebral metabolic shift taking place during sleep that suppresses aerobic glycolysis, a hallmark of environment-oriented waking behavior and synaptic plasticity. Recent studies reveal that glial astrocytes respond to the reduction of wake-promoting neuromodulators by regulating volume, composition and glymphatic drainage of interstitial fluid. These events are accompanied by changes in neuronal discharge patterns, astrocyte-neuron interactions, synaptic transactions and underlying metabolic features. Internally-generated neuronal activity and network homeostasis are proposed to account for the high sleep-related energy demand. Twit Text FOAVip Brain energetics during the sleep-wake cycle ????Curr Opin Neurobiol http://www.kidney.de/pget.php?&tw=1&pmid=29024871 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29024871 #FOAvip English Wikipedia <ref>{{Cite pmid|29024871}}</ref> Brain energetics during the sleep-wake cycle #MMPMID29024871 DiNuzzo M; Nedergaard M Curr Opin Neurobiol 2017[Dec]; 47 (ä): 65-72 PMID29024871show ga Brain activity during wakefulness is associated with high metabolic rates that are believed to support information processing and memory encoding. In spite of loss of consciousness, sleep still carries a substantial energy cost. Experimental evidence supports a cerebral metabolic shift taking place during sleep that suppresses aerobic glycolysis, a hallmark of environment-oriented waking behavior and synaptic plasticity. Recent studies reveal that glial astrocytes respond to the reduction of wake-promoting neuromodulators by regulating volume, composition and glymphatic drainage of interstitial fluid. These events are accompanied by changes in neuronal discharge patterns, astrocyte-neuron interactions, synaptic transactions and underlying metabolic features. Internally-generated neuronal activity and network homeostasis are proposed to account for the high sleep-related energy demand. |Animals[MESH] |Brain/*metabolism[MESH] |Humans[MESH] |Neuroglia/metabolism[MESH] |Neurons/physiology[MESH] |Sleep/*physiology[MESH]Brain energetics during the sleep-wake cycle (epmc).pdf DeepDyve Pubget Overpricing