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10.1002/adhm.201700748 http://scihub22266oqcxt.onion/10.1002/adhm.201700748 28945945!7161897!28945945     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Adv+Healthc+Mater 2017 ; 6 (23): ä Nephropedia Template TP {{tp|p=28945945|t=2017. Macromolecular Antiviral Agents against Zika, Ebola, SARS, and Other Pathogenic Viruses |pdf=|usr=}}{{28945945}} gab.com Text Macromolecular Antiviral Agents against Zika, Ebola, SARS, and Other Pathogenic Viruses JO: Adv Healthc Mater http://www.kidney.de/pget.php?&tw=1&pmid=28945945 #FOAvip Viral pathogens continue to constitute a heavy burden on healthcare and socioeconomic systems. Efforts to create antiviral drugs repeatedly lag behind the advent of pathogens and growing understanding is that broad-spectrum antiviral agents will make strongest impact in future antiviral efforts. This work performs selection of synthetic polymers as novel broadly active agents and demonstrates activity of these polymers against Zika, Ebola, Lassa, Lyssa, Rabies, Marburg, Ebola, influenza, herpes simplex, and human immunodeficiency viruses. Results presented herein offer structure-activity relationships for these pathogens in terms of their susceptibility to inhibition by polymers, and for polymers in terms of their anionic charge and hydrophobicity that make up broad-spectrum antiviral agents. The identified leads cannot be predicted based on prior data on polymer-based antivirals and represent promising candidates for further development as preventive microbicides. Twit Text FOAVip Macromolecular Antiviral Agents against Zika, Ebola, SARS, and Other Pathogenic Viruses ????Adv Healthc Mater http://www.kidney.de/pget.php?&tw=1&pmid=28945945 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28945945 #FOAvip English Wikipedia <ref>{{Cite pmid|28945945}}</ref> Macromolecular Antiviral Agents against Zika, Ebola, SARS, and Other Pathogenic Viruses #MMPMID28945945 Schandock F; Riber CF; Rocker A; Muller JA; Harms M; Gajda P; Zuwala K; Andersen AHF; Lovschall KB; Tolstrup M; Kreppel F; Munch J; Zelikin AN Adv Healthc Mater 2017[Dec]; 6 (23): ä PMID28945945show ga Viral pathogens continue to constitute a heavy burden on healthcare and socioeconomic systems. Efforts to create antiviral drugs repeatedly lag behind the advent of pathogens and growing understanding is that broad-spectrum antiviral agents will make strongest impact in future antiviral efforts. This work performs selection of synthetic polymers as novel broadly active agents and demonstrates activity of these polymers against Zika, Ebola, Lassa, Lyssa, Rabies, Marburg, Ebola, influenza, herpes simplex, and human immunodeficiency viruses. Results presented herein offer structure-activity relationships for these pathogens in terms of their susceptibility to inhibition by polymers, and for polymers in terms of their anionic charge and hydrophobicity that make up broad-spectrum antiviral agents. The identified leads cannot be predicted based on prior data on polymer-based antivirals and represent promising candidates for further development as preventive microbicides. |*Antiviral Agents/chemistry/pharmacology[MESH] |*Polymers/chemistry/pharmacology[MESH] |Animals[MESH] |Chlorocebus aethiops[MESH] |Ebolavirus/*metabolism[MESH] |HEK293 Cells[MESH] |Humans[MESH] |Severe acute respiratory syndrome-related coronavirus/*metabolism[MESH] |Vero Cells[MESH] |Virus Diseases/*drug therapy/metabolism/pathology[MESH]Macromolecular Antiviral Agents against Zika, Ebola, SARS, and Other P(epmc).pdf DeepDyve Pubget Overpricing