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10.1007/BF00543964 http://scihub22266oqcxt.onion/10.1007/BF00543964 2886340!ä!2886340 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Eur+J+Clin+Pharmacol 1987 ; 32 (4): 335-8 Nephropedia Template TP {{tp|p=2886340|t=1987. Magnesium depletion in patients on long-term chlorthalidone therapy for essential hypertension |pdf=|usr=}}{{2886340}} gab.com Text Magnesium depletion in patients on long-term chlorthalidone therapy for essential hypertension JO: Eur J Clin Pharmacol http://www.kidney.de/pget.php?&tw=1&pmid=2886340 #FOAvip Sixty patients were treated for 1 year for essential uncomplicated hypertension, 30 with beta-blockers alone (BB) and 30 with BB and chlorthalidone (CTD). BB did not affect serum K+ or Mg++. In the BB-group there was a statistically significant trend towards retention of Mg++ in a loading test, but the effect was clinically marginal. BB + CTD reduced serum K+ and Mg++ and caused significant Mg++ depletion, as shown by the Mg++ loading test. All the effects were highly significant and were clinically important. The metabolic perturbations due to CTD are potentially dangerous and make this drug unattractive as 'first choice' treatment for hypertension. Twit Text FOAVip Magnesium depletion in patients on long-term chlorthalidone therapy for essential hypertension ????Eur J Clin Pharmacol http://www.kidney.de/pget.php?&tw=1&pmid=2886340 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=2886340 #FOAvip English Wikipedia <ref>{{Cite pmid|2886340}}</ref> Magnesium depletion in patients on long-term chlorthalidone therapy for essential hypertension #MMPMID2886340 Cocco G; Iselin HU; Strozzi C; Cesana B; Baumeler HR Eur J Clin Pharmacol 1987[]; 32 (4): 335-8 PMID2886340show ga Sixty patients were treated for 1 year for essential uncomplicated hypertension, 30 with beta-blockers alone (BB) and 30 with BB and chlorthalidone (CTD). BB did not affect serum K+ or Mg++. In the BB-group there was a statistically significant trend towards retention of Mg++ in a loading test, but the effect was clinically marginal. BB + CTD reduced serum K+ and Mg++ and caused significant Mg++ depletion, as shown by the Mg++ loading test. All the effects were highly significant and were clinically important. The metabolic perturbations due to CTD are potentially dangerous and make this drug unattractive as 'first choice' treatment for hypertension. |Adrenergic beta-Antagonists/adverse effects[MESH] |Adult[MESH] |Aged[MESH] |Chlorthalidone/*adverse effects[MESH] |Drug Therapy, Combination[MESH] |Female[MESH] |Humans[MESH] |Hypertension/*drug therapy[MESH] |Magnesium Deficiency/*chemically induced[MESH] |Magnesium/blood[MESH] |Male[MESH] |Middle Aged[MESH]Magnesium depletion in patients on long-term chlorthalidone therapy fo(epmc).pdf DeepDyve Pubget Overpricing