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10.1111/bjd.15896

http://scihub22266oqcxt.onion/10.1111/bjd.15896
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28832953/?report=reader!5812812!28832953
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suck abstract from ncbi

pmid28832953      Br+J+Dermatol 2018 ; 178 (2): 350-356
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  • Colchicine: an ancient drug with novel applications #MMPMID28832953
  • Dasgeb B; Kornreich D; McGuinn K; Okon L; Brownell I; Sackett DL
  • Br J Dermatol 2018[Feb]; 178 (2): 350-356 PMID28832953show ga
  • Colchicine is a treatment for gout that has been used for more than a millennium. It is the treatment of choice for familial Mediterranean fever and its associated complication, amyloidosis. The 2009 U.S. Food and Drug Administration approval of colchicine as a new drug had research consequences. Recent investigations with large cohorts of patients with gout who have been taking colchicine for years have demonstrated novel applications within oncology, immunology, cardiology and dermatology. Some emerging dermatological uses include the treatment of epidermolysis bullosa acquisita, leucocytoclastic vasculitis, aphthous stomatitis and others. In this work we relate the history and the new horizon of this ancient medicine.
  • |Colchicine/history/pharmacology/*therapeutic use[MESH]
  • |Dermatologic Agents/*therapeutic use[MESH]
  • |Familial Mediterranean Fever/drug therapy[MESH]
  • |Gout Suppressants/history/pharmacology/*therapeutic use[MESH]
  • |Gout/drug therapy/history[MESH]
  • |History, 19th Century[MESH]
  • |History, 21st Century[MESH]
  • |History, Ancient[MESH]
  • |Humans[MESH]
  • |Rheumatic Diseases/drug therapy[MESH]
  • |Skin Diseases/drug therapy[MESH]
  • |Stomatitis, Aphthous/drug therapy[MESH]


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