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10.1089/vim.1987.1.55 http://scihub22266oqcxt.onion/10.1089/vim.1987.1.55 2855699!ä!2855699 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Viral+Immunol 1987 ; 1 (1): 55-68 Nephropedia Template TP {{tp|p=2855699|t=1987. The regulation of herpes simplex virus-specific CTL induction by suppressor cells |pdf=|usr=}}{{2855699}} gab.com Text The regulation of herpes simplex virus-specific CTL induction by suppressor cells JO: Viral Immunol http://www.kidney.de/pget.php?&tw=1&pmid=2855699 #FOAvip The incubation of herpes simplex virus (HSV) immune murine splenocytes with HSV antigens induced suppressor cells which inhibited HSV-specific cytotoxic T lymphocyte (CTL) induction. The cell mediating the suppression was identified as a Thy 1+ Lyt 2+ I-J+ cell. The induction of this suppressor cell required the participation of at least three leukocyte populations. That is, depleting the cultures of either Lyt 1+ or Lyt 2+ splenocytes resulted in a failure to induce suppressor cell activity. Likewise the removal of macrophage-like antigen-presenting cells (APC), in particular I-A- I-J+ APC, abolished suppressor-cell induction. Though the Lyt 2+ I-J+ cells had to be provided by HSV-immune mice, both the APC and the Lyt 1+ cells could be provided by HSV-naive mice. Though the induction of the suppressor cell was virus specific, its action was nonspecific as evidenced by the suppression of influenza-specific CTL induction. The implication of our results for the understanding and manipulation of herpesvirus disease is briefly discussed. Twit Text FOAVip The regulation of herpes simplex virus-specific CTL induction by suppressor cells ????Viral Immunol http://www.kidney.de/pget.php?&tw=1&pmid=2855699 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=2855699 #FOAvip English Wikipedia <ref>{{Cite pmid|2855699}}</ref> The regulation of herpes simplex virus-specific CTL induction by suppressor cells #MMPMID2855699 Horohov DW; Moore RN; Rouse BT Viral Immunol 1987[Spr]; 1 (1): 55-68 PMID2855699show ga The incubation of herpes simplex virus (HSV) immune murine splenocytes with HSV antigens induced suppressor cells which inhibited HSV-specific cytotoxic T lymphocyte (CTL) induction. The cell mediating the suppression was identified as a Thy 1+ Lyt 2+ I-J+ cell. The induction of this suppressor cell required the participation of at least three leukocyte populations. That is, depleting the cultures of either Lyt 1+ or Lyt 2+ splenocytes resulted in a failure to induce suppressor cell activity. Likewise the removal of macrophage-like antigen-presenting cells (APC), in particular I-A- I-J+ APC, abolished suppressor-cell induction. Though the Lyt 2+ I-J+ cells had to be provided by HSV-immune mice, both the APC and the Lyt 1+ cells could be provided by HSV-naive mice. Though the induction of the suppressor cell was virus specific, its action was nonspecific as evidenced by the suppression of influenza-specific CTL induction. The implication of our results for the understanding and manipulation of herpesvirus disease is briefly discussed. |Animals[MESH] |Antigens, Viral/immunology[MESH] |Cyclophosphamide/metabolism[MESH] |Mice[MESH] |Mice, Inbred C3H[MESH] |Simplexvirus/*immunology[MESH] |Spleen/cytology[MESH] |T-Lymphocytes, Cytotoxic/*immunology[MESH]The regulation of herpes simplex virus-specific CTL induction by suppr(epmc).pdf DeepDyve Pubget Overpricing