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Deprecated: Implicit conversion from float 253.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Mater+Sci+Eng+C+Mater+Biol+Appl 2017 ; 75 (ä): 1178-1183 Nephropedia Template TP
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Macrophage phagocytosis of biomedical Mg alloy degradation products prepared by electrochemical method #MMPMID28415404
Zhang J; Hiromoto S; Yamazaki T; Huang H; Jia G; Li H; Yuan G
Mater Sci Eng C Mater Biol Appl 2017[Jun]; 75 (ä): 1178-1183 PMID28415404show ga
Biomedical Mg alloy is promising for its widespread use clinically. In vitro and in vivo studies showed that the degradation products of biomedical Mg alloy were composed of O, P, Ca, Mg and other alloying elements. However, little is known about the metabolism of the degradation products. In this study, the in vitro macrophage phagocytosis of the degradation products of a biomedical Mg-Nd-Zn-Zr alloy was directly observed. This result affirms the necessity to investigate the long-term fate of Mg alloy degradation products in physiological environments. Besides, an electrochemical method was proposed to prepare enough amount of degradation products in vitro efficiently.