Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText.
Kick-your-searchterm to multiple Engines kick-your-query now !>
A dictionary by aggregated review articles of nephrology, medicine and the life sciences
Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.
garesp_yesshow ga

suck pdf from google scholar
unlimited free pdf from europmc28324465    free
PDF from PMC    free
html from PMC    free
PDF vom PMID28324465  :  Publisher
Nephropedia Template TP Text

Twit Text FOAVip

Twit Text #

English Wikipedia

  • Incidence of constitutive and inducible clindamycin resistance among hospital-associated Staphylococcus aureus #MMPMID28324465
  • Sasirekha B; Usha MS; Amruta JA; Ankit S; Brinda N; Divya R
  • 3 Biotech 2014[Feb]; 4 (1): 85-89 PMID28324465garesp_yesshow ga
  • Clindamycin is one of the important alternative antibiotics in the therapy of Staphylococcus aureus infections. Clinical failure of clindamycin therapy has been reported due to multiple mechanisms that confer resistance to macrolides, lincosamides and Streptogramin B (MLSB) antibiotics. In vitro routine tests for clindamycin susceptibility may fail to detect inducible clindamycin resistance due to erm genes, resulting in the treatment failure. Although data from the developed countries have shown to be enormity of the problem, data from the developing countries are lacking. The aim of the study was to distinguish different resistance phenotypes in erythromycin-resistant S. aureus by a simple double-disc diffusion test (D test). A total of 153 S. aureus isolates were subjected to routine antibiotic susceptibility testing, including cefoxitin disc (30 mug) and by oxacillin screen agar. Inducible clindamycin resistance was tested by 'D test' as per CLSI guidelines. Odds ratios (OR) and 95 % confidence intervals (95 % CI) were calculated. P values were calculated using SPSS (version 18). Among 153 S. aureus isolates, 42 (27.45 %) were resistant to methicillin, whereas 111 (72.54 %) were methicillin susceptible. Out of the 63 (41.17 %) erythromycin-resistant S. aureus isolates, 14 (9.15 %) showed inducible resistance [P = 0.0002, odds ratio (OR) 18.30; 95 % confidence interval (CI) 8.72-25.77), 20 (13.07 %)] showed constitutive resistance (P = 0.002, OR 14.38, 95 % CI 5.33-21.49), while the remaining 29 (18.95 %) showed inducible phenotype. Inducible and constitutive resistance was found to be higher in MSSA when compared with MRSA. Clinical laboratories should perform D test routinely to guide the clinicians about the inducible clindamycin resistance and to prevent misuse of antibiotics.
  • ä

  • DeepDyve
  • Pubget Overpricing
  • garesp_yesshow ga

    85 1.4 2014