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10.1111/febs.13997

http://scihub22266oqcxt.onion/10.1111/febs.13997
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28121076!ä!28121076

suck abstract from ncbi

pmid28121076      FEBS+J 2017 ; 284 (2): 218-221
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  • Targeting a metabolic pathway to fight the flu #MMPMID28121076
  • Boergeling Y; Ludwig S
  • FEBS J 2017[Jan]; 284 (2): 218-221 PMID28121076show ga
  • Our antiviral arsenal to fight influenza viruses is limited and we need novel anti-flu drugs. Recently, cellular drug targets came into focus and omics analysis were instrumental to suggest candidate factors. In this issue of The FEBS Journal, Kainov and colleagues used transcriptome data to investigate virus-induced changes in tryptophan metabolism that may serve as immunomodulatory approach against viruses.
  • |Antiviral Agents/*pharmacology[MESH]
  • |Host-Pathogen Interactions[MESH]
  • |Humans[MESH]
  • |Immunologic Factors/*pharmacology[MESH]
  • |Indoleamine-Pyrrole 2,3,-Dioxygenase/genetics/immunology[MESH]
  • |Influenza, Human/*drug therapy/immunology/pathology/virology[MESH]
  • |Interferons/genetics/immunology[MESH]
  • |Kynurenine/*antagonists & inhibitors/biosynthesis[MESH]
  • |Macrophages/drug effects/virology[MESH]
  • |Metabolic Networks and Pathways/*drug effects/genetics/immunology[MESH]
  • |Orthomyxoviridae/genetics/growth & development/*metabolism[MESH]
  • |Transcriptome[MESH]


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