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10.1002/jcp.25766 http://scihub22266oqcxt.onion/10.1002/jcp.25766 28063231!7166392!28063231     free     free     free Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Cell+Physiol 2017 ; 232 (7): 1660-1668 Nephropedia Template TP {{tp|p=28063231|t=2017. Exosomes: Nanoparticulate tools for RNA interference and drug delivery |pdf=|usr=}}{{28063231}} gab.com Text Exosomes: Nanoparticulate tools for RNA interference and drug delivery JO: J Cell Physiol http://www.kidney.de/pget.php?&tw=1&pmid=28063231 #FOAvip Exosomes are naturally occurring extracellular vesicles released by most mammalian cells in all body fluids. Exosomes are known as key mediators in cell-cell communication and facilitate the transfer of genetic and biochemical information between distant cells. Structurally, exosomes are composed of lipids, proteins, and also several types of RNAs which enable these vesicles to serve as important disease biomarkers. Moreover, exosomes have emerged as novel drug and gene delivery tools owing to their multiple advantages over conventional delivery systems. Recently, increasing attention has been focused on exosomes for the delivery of drugs, including therapeutic recombinant proteins, to various target tissues. Exosomes are also promising vehicles for the delivery of microRNAs and small interfering RNAs, which is usually hampered by rapid degradation of these RNAs, as well as inefficient tissue specificity of currently available delivery strategies. This review highlights the most recent accomplishments and trends in the use of exosomes for the delivery of drugs and therapeutic RNA molecules. Twit Text FOAVip Exosomes: Nanoparticulate tools for RNA interference and drug delivery ????J Cell Physiol http://www.kidney.de/pget.php?&tw=1&pmid=28063231 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28063231 #FOAvip English Wikipedia <ref>{{Cite pmid|28063231}}</ref> Exosomes: Nanoparticulate tools for RNA interference and drug delivery #MMPMID28063231 Shahabipour F; Barati N; Johnston TP; Derosa G; Maffioli P; Sahebkar A J Cell Physiol 2017[Jul]; 232 (7): 1660-1668 PMID28063231show ga Exosomes are naturally occurring extracellular vesicles released by most mammalian cells in all body fluids. Exosomes are known as key mediators in cell-cell communication and facilitate the transfer of genetic and biochemical information between distant cells. Structurally, exosomes are composed of lipids, proteins, and also several types of RNAs which enable these vesicles to serve as important disease biomarkers. Moreover, exosomes have emerged as novel drug and gene delivery tools owing to their multiple advantages over conventional delivery systems. Recently, increasing attention has been focused on exosomes for the delivery of drugs, including therapeutic recombinant proteins, to various target tissues. Exosomes are also promising vehicles for the delivery of microRNAs and small interfering RNAs, which is usually hampered by rapid degradation of these RNAs, as well as inefficient tissue specificity of currently available delivery strategies. This review highlights the most recent accomplishments and trends in the use of exosomes for the delivery of drugs and therapeutic RNA molecules. |*Drug Delivery Systems[MESH] |*RNA Interference[MESH] |Animals[MESH] |Drug Carriers/chemistry[MESH] |Exosomes/*metabolism[MESH] |Humans[MESH] |Nanoparticles/*chemistry[MESH]Exosomes: Nanoparticulate tools for RNA interference and drug delivery(epmc).pdf DeepDyve Pubget Overpricing