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10.1155/2016/4986797

http://scihub22266oqcxt.onion/10.1155/2016/4986797
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27868073!5102737!27868073
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suck abstract from ncbi

pmid27868073      J+Immunol+Res 2016 ; 2016 (?): 4986797
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  • The Crosstalk between Myeloid Derived Suppressor Cells and Immune Cells: To Establish Immune Tolerance in Transplantation #MMPMID27868073
  • Zhang C; Wang S; Yang C; Rong R
  • J Immunol Res 2016[]; 2016 (?): 4986797 PMID27868073show ga
  • Myeloid derived suppressor cells (MDSCs) are a heterogeneous population of myeloid precursor and progenitor cells and endowed with a robust immunosuppressive activity in multiple pathophysiological conditions. Recent studies have uncovered the crosstalk between MDSCs and immune cells (i.e., natural killer cells, dendritic cells, macrophages, natural killer T cells, and regulatory T cells) and its role in the establishment and maintenance of immune tolerant microenvironment in transplantation. Considering their strong immunosuppressive capability, MDSCs could become a prospective clinical regimen during transplantation tolerance induction, resulting in long-term graft survival with decreased or without immunosuppressive drugs. The review summarized recent research advances in this field and looked ahead at the research directions in the future.
  • |*Receptor Cross-Talk/immunology[MESH]
  • |*Transplantation Tolerance[MESH]
  • |Adaptive Immunity[MESH]
  • |Animals[MESH]
  • |Dendritic Cells/immunology[MESH]
  • |Humans[MESH]
  • |Killer Cells, Natural/immunology[MESH]
  • |Macrophages/immunology[MESH]
  • |Mice[MESH]
  • |Myeloid-Derived Suppressor Cells/*immunology[MESH]
  • |Natural Killer T-Cells/immunology[MESH]


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