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10.1002/ejhf.665 http://scihub22266oqcxt.onion/10.1002/ejhf.665 27748022!ä!27748022 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Eur+J+Heart+Fail 2016 ; 18 (12): 1430-1441 Nephropedia Template TP {{tp|p=27748022|t=2016. Relevance of cardiac parvovirus B19 in myocarditis and dilated cardiomyopathy: review of the literature |pdf=|usr=}}{{27748022}} gab.com Text Relevance of cardiac parvovirus B19 in myocarditis and dilated cardiomyopathy: review of the literature JO: Eur J Heart Fail http://www.kidney.de/pget.php?&tw=1&pmid=27748022 #FOAvip Over the last decade, parvovirus B19 (B19V) has frequently been linked to the pathogenesis of myocarditis (MC) and its progression towards dilated cardiomyopathy (DCM). The exact role of the presence of B19V and its load remains controversial, as this virus is also found in the heart of healthy subjects. Moreover, the prognostic relevance of B19V prevalence in endomyocardial biopsies still remains unclear. As a result, it is unclear whether the presence of B19V should be treated. This review provides an overview of recent literature investigating the presence of B19V and its pathophysiological relevance in MC and DCM, as well as in normal hearts. In brief, no difference in B19V prevalence is observed between MC/DCM and healthy control hearts. Therefore, the question remains open whether and how cardiac B19V may be of pathogenetic importance. Findings suggest that B19V is aetiologically relevant either in the presence of other cardiotropic viruses, or when B19V load is high and/or actively replicating, which both may maintain myocardial (low-grade) inflammation. Therefore, future studies should focus on the prognostic relevance of the viral load, replicative status and virus co-infections. In addition, the immunogenetic background of MC/DCM patients that makes them susceptible to develop heart failure upon presence of B19V should be more thoroughly investigated. Twit Text FOAVip Relevance of cardiac parvovirus B19 in myocarditis and dilated cardiomyopathy: review of the literature ????Eur J Heart Fail http://www.kidney.de/pget.php?&tw=1&pmid=27748022 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27748022 #FOAvip English Wikipedia <ref>{{Cite pmid|27748022}}</ref> Relevance of cardiac parvovirus B19 in myocarditis and dilated cardiomyopathy: review of the literature #MMPMID27748022 Verdonschot J; Hazebroek M; Merken J; Debing Y; Dennert R; Brunner-La Rocca HP; Heymans S Eur J Heart Fail 2016[Dec]; 18 (12): 1430-1441 PMID27748022show ga Over the last decade, parvovirus B19 (B19V) has frequently been linked to the pathogenesis of myocarditis (MC) and its progression towards dilated cardiomyopathy (DCM). The exact role of the presence of B19V and its load remains controversial, as this virus is also found in the heart of healthy subjects. Moreover, the prognostic relevance of B19V prevalence in endomyocardial biopsies still remains unclear. As a result, it is unclear whether the presence of B19V should be treated. This review provides an overview of recent literature investigating the presence of B19V and its pathophysiological relevance in MC and DCM, as well as in normal hearts. In brief, no difference in B19V prevalence is observed between MC/DCM and healthy control hearts. Therefore, the question remains open whether and how cardiac B19V may be of pathogenetic importance. Findings suggest that B19V is aetiologically relevant either in the presence of other cardiotropic viruses, or when B19V load is high and/or actively replicating, which both may maintain myocardial (low-grade) inflammation. Therefore, future studies should focus on the prognostic relevance of the viral load, replicative status and virus co-infections. In addition, the immunogenetic background of MC/DCM patients that makes them susceptible to develop heart failure upon presence of B19V should be more thoroughly investigated. |*Parvovirus B19, Human[MESH] |Biopsy[MESH] |Cardiomyopathy, Dilated/*epidemiology/virology[MESH] |Heart/*virology[MESH] |Humans[MESH] |Myocarditis/*epidemiology/virology[MESH] |Myocardium/pathology[MESH] |Parvoviridae Infections/*epidemiology[MESH]Relevance of cardiac parvovirus B19 in myocarditis and dilated cardiom(epmc).pdf DeepDyve Pubget Overpricing